| US 7,522,744 B2 | ||
| System and method for adaptive bolus chasing computed tomography (CT) angiography | ||
| Er-wei Bai, Iowa City, Iowa (US); Ge Wang, Iowa City, Iowa (US); and Michael W. Vannier, Iowa City, Iowa (US) | ||
| Assigned to University of Iowa Research Foundation, Iowa City, Iowa (US) | ||
| Filed on Aug. 29, 2005, as Appl. No. 11/215,733. | ||
| Claims priority of provisional application 60/605865, filed on Aug. 31, 2004. | ||
| Prior Publication US 2006/0178836 A1, Aug. 10, 2006 | ||
| Int. Cl. G06K 9/00 (2006.01); G06F 19/00 (2006.01); A61B 6/00 (2006.01) | ||
| U.S. Cl. 382—100 [702/19; 378/4] | 68 Claims |
| 1. A method of utilizing bolus propagation and control for contrast enhancement comprising:
measuring with an imaging device a position of a bolus moving along a path in a biological structure;
predicting a future position of the bolus using a simplified target model, wherein the simplified target model is a non-parametric
model and wherein predicting the future position of the bolus comprises estimating the future position by pb((i+1)Δt)=pb(iΔt)+v(iΔt)Δt, wherein v(iΔt) and pb(iΔt)denote an estimate of the bolus velocity and position v(iΔt) and pb(iΔt) at time iΔt, respectively;
comparing the predicted future position of the bolus with the measured position of the bolus;
determining a control action to eliminate a discrepancy, if any, between the predicted position of the bolus and the measured
position of the bolus; and
adaptively adjusting the relative position of the imaging device and the biological structure according to the control action
to chase the motion of the bolus.
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