US 7,521,580 B1
Non-cytotoxic synthetic analogues of (1E, 6E)-1, 7-Bis (4-hydroxy-3-methoxyphenyl)-1, 6-heptadiene-3, 5-Dione and therapeutic applications thereof in cystic fibrosis
Muhammed Majeed, Piscataway, N.J. (US); Rajinder Kumar Bammi, Bangalore (India); Natarajan Sankaran, Bangalore (India); Subbalakshmi Prakash, Piscataway, N.J. (US); Kalyanam Nagabhushanam, Piscataway, N.J. (US); Samuel Manoharan Thomas, Bangalore (India); Susmitha Anand, Bangalore (India); and Geetha Kanhangad-Gangadharan, Bangalore (India)
Assigned to Sami Labs Ltd., Bangalore (India)
Filed on Feb. 18, 2008, as Appl. No. 12/32,955.
Int. Cl. C07C 49/203 (2006.01); C07C 49/215 (2006.01); A61K 31/12 (2006.01)
U.S. Cl. 568—325  [514/679] 8 Claims
 
1. A pharmacological interventional molecule for cystic fibrosis therapy represented by the general formula (STR#1), wherein the phenolic hydroxyl group is flanked by alkyl groups branched at α-carbon position,

OG Complex Work Unit Drawing