US 7,517,524 B2
	Immunointeractive molecules
Andrew Nash, Kew (Australia); Giuseppe Maccarone, Pascoe Vale (Australia); and Pierre David Scotney, Greensborough (Australia)
Assigned to Zenyth Operations Pty Ltd, (Australia)
Filed on Jan. 12, 2007, as Appl. No. 11/652,711.
Application 11/652711 is a continuation of application No. 10/440295, filed on May 16, 2003, abandoned.
Claims priority of provisional application 60/381285, filed on May 17, 2002.
Prior Publication US 2007/0128197 A1, Jun. 07, 2007
Int. Cl. A61K 39/395 (2006.01); C12P 21/08 (2006.01); C07K 16/00 (2006.01); C07K 16/18 (2006.01); C07K 16/22 (2006.01)

U.S. Cl. 424—130.1  [424/133.1; 424/141.1; 424/142.1; 424/145.1; 435/70.21; 530/387.1; 530/387.3; 530/388.15; 530/388.25]

6 Claims

1. An isolated monoclonal antibody or an antigen-binding fragment thereof which binds to human VEGF-B, wherein said antibody is 2H10 produced by the hybridoma deposited at the American Type Culture Collection (ATCC) as PTA-6889, and the binding of the antibody or the fragment thereof to human VEGF-B antagonizes binding between human VEGF-B and VEGF-R1.