US 7,517,439 B2
Error detection in analyte measurements based on measurement of system resistance
Ian Harding, Somerville, Mass. (US); Richard Williams, Cambridge, Mass. (US); and Steven Diamond, Somerville, Mass. (US)
Assigned to AgaMatrix, Inc., Salem, N.H. (US)
Filed on Apr. 15, 2005, as Appl. No. 10/907,817.
Prior Publication US 2006/0231424 A1, Oct. 19, 2006
Int. Cl. G01F 1/64 (2006.01)
U.S. Cl. 204—401  [204/792; 204/777] 8 Claims
OG exemplary drawing
 
1. A method for determination of an analyte in a sample comprising the steps of:
(a) introducing the sample to an electrochemical test strip having working and counter electrodes;
(b) applying a potential difference, Vapp, between the electrodes of the test strip and observing a current signal sufficient to provide a determination of analyte in the sample;
(c) switching off the applied potential at time tswitch, and determining the magnitude, Vdrop, of a voltage drop occurring immediately after tswitch, wherein the magnitude of Vdrop, if present, is indicative of the magnitude of series electrode resistance;
(d) checking the determined magnitude of Vdrop against a predetermined range, and rejecting the test if the magnitude of Vdrop falls outside of the range, and
(e) if the magnitude is within the predetermined range, proceeding to display or communicate the result from the determination of analyte.