US 7,514,076 B2
	Antitumor agents
Hiroshi Maeda, 3-21-24, Koto, Kumamoto-shi, Kumamoto (Japan); Tomohiro Sawa, Kumamoto (Japan); and Takaaki Akaike, Kumamoto (Japan)
Assigned to Hiroshi Maeda, Kumamoto (Japan)
Filed on Jul. 14, 2006, as Appl. No. 11/485,970.
Application 11/485970 is a division of application No. 10/314439, filed on Dec. 09, 2002, abandoned.
Application 09/536017 is a division of application No. 09/136522, filed on Aug. 19, 1998, abandoned.
Application 10/314439 is a continuation in part of application No. 09/536017, filed on Mar. 27, 2000, granted, now 6,716,426.
Claims priority of application No. 9-240235 (JP), filed on Aug. 22, 1997.
Prior Publication US 2006/0251640 A1, Nov. 09, 2006
Int. Cl. A61K 38/44 (2006.01); A61K 47/34 (2006.01)

U.S. Cl. 424—94.4  [424/94.3; 424/193.1; 435/190; 514/2]

3 Claims

1. A method for treating tumors, which comprises administering to a patient in need thereof a therapeutically effective amount of D-amino acid oxidase which is chemically conjugated with a polymer, and then 6 to 100 hours thereafter administering D-amino acid which is a substrate for the D-amino acid oxidase.