| US 7,514,074 B2 | ||
| Cardiac muscle regeneration using mesenchymal stem cells | ||
| Mark F. Pittenger, Severna Park, Md. (US); Stephen L. Gordon, Columbia, Md. (US); Alastair Morgan Mackay, Timonium, Md. (US); and Bradley J. Martin, Ellicot City, Md. (US) | ||
| Assigned to Osiris Therapeutics, Inc., Baltimore, Md. (US) | ||
| Filed on Oct. 21, 2003, as Appl. No. 10/690,435. | ||
| Application 10/690435 is a continuation in part of application No. 10/278148, filed on Oct. 22, 2002, abandoned. | ||
| Application 10/278148 is a continuation in part of application No. 10/127737, filed on Apr. 22, 2002, abandoned. | ||
| Application 10/127737 is a continuation of application No. 09/446952, granted, now 6,387,369, previously published as PCT/US98/14520, filed on Jul. 14, 1998. | ||
| Claims priority of provisional application 60/052910, filed on Jul. 14, 1997. | ||
| Prior Publication US 2005/0112104 A1, May 26, 2005 | ||
| This patent is subject to a terminal disclaimer. | ||
| Int. Cl. A01N 65/00 (2006.01); C12N 5/00 (2006.01) | ||
| U.S. Cl. 424—93.1 [424/93.7; 435/377] | 7 Claims |
| 1. A method of improving ventricular wall motion of the heart of an individual, comprising:
administering to said individual autologous or allogeneic mesenchymal stem cells, wherein said mesenchymal stem cells are
administered in an amount effective to improve ventricular wall motion of the heart of said individual.
|