	US 7,513,619 B2
	High resolution laterial and axial tomography
François Lacombe, Chaville (France); David Lafaille, Meudon (France); Marie Glanc, Meudon (France); and Eric Gendron, Meudon (France)
Assigned to Centre National de la Recherche Scientifique, Paris (France); Observatoire de Paris, Paris (France); and Mauna Kea Technologies, Paris (France)
Appl. No. 10/586,716 PCT Filed Jan. 21, 2005, PCT No. PCT/FR2005/000132 § 371(c)(1), (2), (4) Date Jul. 20, 2006, PCT Pub. No. WO2005/080911, PCT Pub. Date Sep. 01, 2005.
Claims priority of application No. 04 00582 (FR), filed on Jan. 22, 2004.
Prior Publication US 2008/0231807 A1, Sep. 25, 2008
Int. Cl. A61B 3/10 (2006.01); G01B 11/02 (2006.01)

U.S. Cl. 351—205 [351/221; 351/246; 356/497; 378/21]

34 Claims

1. An in vivo tomography system with high axial and lateral resolution of the human retina, comprising:

a Michelson interferometer, producing a full-field tomography setup by interference at coherence length (OCT) with a Z scanning,

an input light source arranged in an input arm of the interferometer,

adaptive optical means, designed to correct wavefronts originating from the eye and directed to the eye, comprising a reference source, a deformable mirror and means of analysing the wave surface,

means of detection, arranged in an imaging arm of the interferometer, designed to produce an image from an interferometric measurement according to the OCT principle, and

means of adjusting the focussing of the means of analysis of the wave surface,

wherein the means of adjusting the focussing are arranged to force the deformable mirror to adopt an additional curvature, so as to conjugate the input light source and the means of detection with a point at a predetermined depth in the retina, said means of adjustment being controlled in synchronism with the Z scanning of the OCT tomography setup.