US 7,351,739 B2
Bioactive compounds and methods of uses thereof
Chi-Tang Ho, East Brunswick, N.J. (US); Naisheng Bai, Highland Park, N.J. (US); Zigang Dong, Rochester, Minn. (US); Ann M. Bode, Cannon Falls, Minn. (US); and Slavik Dushenkov, Fort Lee, N.J. (US)
Assigned to Wellgen, Inc., New Brunswick, N.J. (US); The Regents of the University of Minnesota, Minneapolis, Minn. (US); and Rutgers, the State University of New Jersey, New Brunswick, N.J. (US)
Filed on Apr. 29, 2005, as Appl. No. 11/118,915.
Claims priority of provisional application 60/567340, filed on Apr. 30, 2004.
Prior Publication US 2006/0052438 A1, Mar. 09, 2006
Int. Cl. A01N 43/20 (2006.01); A01N 43/24 (2006.01); A61K 31/335 (2006.01); C07D 303/00 (2006.01); C07D 305/14 (2006.01)
U.S. Cl. 514—475  [549/332] 9 Claims
 
1. A compound having the formula (I):

OG Complex Work Unit Drawing
or a pharmaceutically acceptable salt, or solvate, thereof, wherein:
R1, R2, R3 and R4 are each independently hydrogen, (C1-C6)alkyl, or (C1-C12)acyl;
R5, R6, R7, R8, R9, R10, R11, R12, and R13 are each independently hydrogen or (C1-C6)alkyl; and
R14 and R15 are each independently hydrogen or (C1-C6) alkyl.