US 7,511,078 B2
Antiallergic agents, drugs, foods, drinks or cosmetics containing them and process for producing the same
Taichi Yamamoto, Noda (Japan); Tomoko Kanamori, Noda (Japan); Fumio Yamaguchi, Noda (Japan); Makoto Saito, Noda (Japan); Ryohei Tsuji, Noda (Japan); and Akio Obata, Noda (Japan)
Assigned to Kikkoman Corporation, Noda-shi (Japan)
Appl. No. 10/312,504
PCT Filed Jun. 28, 2001, PCT No. PCT/JP01/05553
§ 371(c)(1), (2), (4) Date Dec. 27, 2002,
PCT Pub. No. WO02/00239, PCT Pub. Date Jan. 03, 2002.
Prior Publication US 2003/0138511 A1, Jul. 24, 2003
Int. Cl. A61K 31/12 (2006.01); A61K 35/78 (2006.01)
U.S. Cl. 514—679  [424/777] 5 Claims
 
1. A method of treating allergies or an allergic reaction, said method comprising:
administering an effective amount of a pharmaceutical composition comprising at least two isolated or purified compounds selected from the group consisting of a naringenin chalcone, a tricaffeoylquinic acid and a dicaffeoylsuccinylquinic acid as active ingredients or a pharmacologically acceptable salt or ester of any of said active ingredients to a patient in need thereof, wherein said active ingredients are administered in a total amount of about 0.1 to 1,000 mg per day, wherein said allergy or allergic reaction is at least one selected from the group consisting of atopic dermatitis, allergic rhinitis, pollinosis, allergic asthma and a food allergy.