US 7,507,765 B2
Geranyl compounds
Kiyoshi Akiyama, Komatsu (Japan)
Assigned to Ohgen Research Laboratories, Ltd., Ishikawa (Japan)
Filed on Feb. 17, 2006, as Appl. No. 11/356,019.
Application 11/356019 is a division of application No. 10/498882, granted, now 7,125,852, previously published as PCT/JP02/13615, filed on Dec. 26, 2002.
Claims priority of application No. 2002-4123 (JP), filed on Jan. 11, 2002; application No. 2002-4131 (JP), filed on Jan. 11, 2002; application No. 2002-4136 (JP), filed on Jan. 11, 2002; and application No. 2002-283644 (JP), filed on Sep. 27, 2002.
Prior Publication US 2006/0142244 A1, Jun. 29, 2006
Int. Cl. A01N 37/12 (2006.01); A01N 37/44 (2006.01); A61K 31/195 (2006.01)
U.S. Cl. 514—563  [514/561] 5 Claims
 
1. A geranyl compound represented by the following formula (I-2):

OG Complex Work Unit Drawing
in which R2 stands for a residual group remaining after removing all carboxyl groups present in a carboxylic acid selected from the group consisting of malic acid, citric acid, succinic acid, fumaric acid, 2-oxoglutaric acid, pyruvic acid, p-pyruvoaminobenzoic acid, retinoic acid, tyrosine, cysteine, glutamic acid and serine, and where hydroxyl or amino group(s) are present in the residual group, they may optionally be protected by acyl or benzyloxycarbonyl group(s),
m is 1, 2 or 3,
n is 0, 1 or 2, and
m +n represents the number of carboxyl groups which are removed from said carboxylic acid.