| US 7,345,091 B2 | ||
| Carotenoid ether analogs or derivatives for the inhibition and amelioration of disease | ||
| Samuel Fournier Lockwood, Lake Linden, Mich. (US); Sean O'Malley, Honolulu, Hi. (US); David G. Watumull, Honolulu, Hi. (US); Laura M. Hix, San Francisco, Calif. (US); Henry Jackson, Honolulu, Hi. (US); and Geoff Nadolski, Kaaawa, Hi. (US) | ||
| Assigned to Cardax Pharmaceuticals, Inc., Aiea, Hi. (US) | ||
| Filed on Mar. 04, 2004, as Appl. No. 10/793,671. | ||
| Application 10/793671 is a continuation in part of application No. 10/629538, filed on Jul. 29, 2003, granted, now 7,145,025. | ||
| Claims priority of provisional application 60/485304, filed on Jul. 03, 2003. | ||
| Claims priority of provisional application 60/473741, filed on May 28, 2003. | ||
| Claims priority of provisional application 60/472831, filed on May 22, 2003. | ||
| Claims priority of provisional application 60/467973, filed on May 05, 2003. | ||
| Claims priority of provisional application 60/399194, filed on Jul. 29, 2002. | ||
| Prior Publication US 2005/0009758 A1, Jan. 13, 2005 | ||
| Int. Cl. A61K 31/341 (2006.01); A61K 31/351 (2006.01) | ||
| U.S. Cl. 514—460 [514/473] | 16 Claims |
1. A composition comprising a chemical compound having the structure
 where each R3 is independently hydrogen or methyl;
where each Y is independently O or H2;
where each X is independently
  where each R1 is independently -alkyl-NR23+, -aryl-NR23+, -alkyl-CO2−, -aryl-CO2−, -alkyl-CO2H; -alkyl-CO2R6; amino acid-NH2, -amino acid-NH3+, -phosphorylated amino acid-NH3+, polyethylene glycol, dextran, H, alkyl, aryl, or alkali salt;
where each R2 is independently H, alkyl, or aryl; and
where each R5 is independently H, alkyl, benzyl, or alkali salt.
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