| US 7,501,533 B2 | ||
| Process for preparing lysophosphatidylcholine | ||
| Lorenzo De Ferra, Patrica (Italy); Stefano Servi, Milan (Italy); Ezio Fasoli, Milan (Italy); Mauro Anibaldi, Patrica (Italy); and Daniele Scorretti, Patrica (Italy) | ||
| Assigned to Chem SpA, Cinisello Balsamo (Milan) (Italy) | ||
| Filed on Dec. 06, 2005, as Appl. No. 11/244,395. | ||
| Claims priority of application No. MI2004A1941 (IT), filed on Oct. 13, 2004. | ||
| Prior Publication US 2006/0079703 A1, Apr. 13, 2006 | ||
| Int. Cl. C07F 9/02 (2006.01) | ||
| U.S. Cl. 554—82 [554/168; 556/87] | 44 Claims |
| 1. A process for preparing lysophosphatidylcholine, comprising selectively monoacylating glycerophosphorylcholine at position sn-1 with an acylating agent in the presence of a dialkyltin derivative in which said dialkyltin derivative has two alkyl groups bound to the tin atom, said groups being identical to or different from each other, containing from 1 to 18 carbon atoms or polymeric in nature, and two halogens or two alkoxy or acyloxy groups or an oxygen atom bound by a double bond. |