| US 7,501,526 B2 | ||
| Synthesis of polyamine compounds | ||
| Chien-Huang Wu, Taipei County (Taiwan); Jia-Liang Zhu, Taipei (Taiwan); Chen-Tso Tseng, Taipei (Taiwan); Chi-Feng Yen, Taipei (Taiwan); Kak-Shan Shia, Taipei (Taiwan); Yibin Xiang, Acton, Mass. (US); Gholam Hossein Hakimelahi, Taipei (Taiwan); and Ming-Chen Chou, Taipei (Taiwan) | ||
| Assigned to Taigen Biotechnology, Taipei (Taiwan) | ||
| Filed on Jan. 20, 2005, as Appl. No. 11/39,283. | ||
| Prior Publication US 2006/0160860 A1, Jul. 20, 2006 | ||
| Int. Cl. C07D 235/06 (2006.01); C07D 235/10 (2006.01) | ||
| U.S. Cl. 548—309.7 [548/310.4] | 19 Claims |
1. A compound of formula (V):
 R1 is heteroaryl, aryl, C3-C8 cycloalkyl, or C3-C8 heterocycloalkyl;
R2 is H or an amino-protecting group; and
each of R4, R5, and R6, independently, is H, OR′, halogen, C1-C10 alkyl, C3-C8 cycloalkyl, C3-C8 heterocycloalkyl, heteroaryl, or aryl; in which R′ is H, C1-C10 alkyl, C3-C8 cycloalkyl, C3-C8 heterocycloalkyl, aryl, or heteroaryl; at most two of R4, R5, and R6 being H.
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