US 7,501,453 B2
Cyclopropanes with central nervous system activity
Huw M. L. Davies, E. Amherst, N.Y. (US); and Timothy Gregg, Williamsville, N.Y. (US)
Assigned to The Research Foundation of State University of New York, Amherst, N.Y. (US)
Filed on Mar. 12, 2007, as Appl. No. 11/716,884.
Claims priority of provisional application 60/781245, filed on Mar. 10, 2006.
Prior Publication US 2007/0244201 A1, Oct. 18, 2007
Int. Cl. A61K 31/137 (2006.01); C07C 211/40 (2006.01)
U.S. Cl. 514—650  [564/306] 12 Claims
 
1. A compound having the following structure:

OG Complex Work Unit Drawing
or its enantiomer, wherein R1 is an alkane of 3 carbons or less, R2 consists of one or more substituents selected from the group consisting of hydrogen, halogen, alkane of 3 carbons or less, and adjacent ring forming a naphthyl group, and R3 consists of one or more substituents selected from the group consisting of hydrogen, halogen, alkane of 3 carbons or less, and adjacent ring forming a naphthyl group.