US 7,501,135 B2
Gastric acid secretion
John Hakkinen, North Stonington, Conn. (US); Roelof Marthinus Horak, Pretoria (South Africa); and Vinesh Maharaj, Pretoria (South Africa)
Assigned to Conopco, Inc., Englewood Cliffs, N.J. (US)
Filed on Aug. 19, 2004, as Appl. No. 10/921,364.
Application 10/171640 is a division of application No. 09/691582, filed on Oct. 18, 2000, granted, now 6,488,967.
Application 10/921364 is a continuation of application No. 10/171640, filed on Jun. 17, 2002, granted, now 6,808,723.
Claims priority of application No. 9925457.5 (GB), filed on Oct. 27, 1999.
Prior Publication US 2005/0079233 A1, Apr. 14, 2005
This patent is subject to a terminal disclaimer.
Int. Cl. A61K 35/78 (2006.01)
U.S. Cl. 424—725  [514/925] 7 Claims
 
1. A method of reducing gastric acid secretion in an animal, comprising administering to said animal in need thereof an effective amount of either:
(a) an extract of a plant of the genus Hoodia or Trichocaulon; or
(b) a compound of the formula

OG Complex Work Unit Drawing
wherein:
R=an alkyl group containing from one to four carbon atoms;
R1=H, an alkyl group containing from one to four carbon atoms, or an organic ester group;
R2=H, or one or more 6-deoxy carbohydrates, or one or more 2,6-dideoxy carbohydrates, or glucose, or a combination thereof;
and in which the dashed bonds indicate the optional presence of a double bond at the C4-C5 position or the C5-C6 position.