in which:

R₁ represents a hydrogen atom or a (C₁-C₄)alkyl group which is unsubstituted or substituted with one or more fluorine atoms;

R₂ represents:

either a homopiperidin-1-yl, piperidin-1-yl, pyrrolidin-1-yl or azetidin-1-yl radical, said radicals being unsubstituted or substituted once or twice with a substituent, each chosen independently from a fluorine atom, a (C₁-C₄)alkyl, (C₁-C₄)alkoxyl, trifluoromethyl, —OCF₃, CH₂OH, —CONH₂ or a phenyl group, said phenyl group being unsubstituted or substituted once or twice with a substituent, each chosen independently from a halogen atom, a —CF₃ group, a methoxyl group or a trifluoromethoxyl group;

or an amino(C₁-C₆)alkyl group which is unsubstituted or substituted with one or more substituents, each chosen independently from a fluorine atom, a hydroxyl group, a —CONH₂ group or a phenyl group, said phenyl group being unsubstituted or substituted once or twice with a substituent, each chosen independently from a halogen atom, a —CF₃ group, a methoxyl group or a trifluoromethoxyl group;

or R₁ and R₂, together with the nitrogen atom to which they are attached, constitute:

either a piperazin-1-yl or 1,4-diazepan-1-yl radical, said radicals being unsubstituted or substituted with a substituent chosen from a phenyl, benzodioxolyl, benzodioxolylmethyl, tetrahydrofuranylcarbonyl, —COR₁₁, or —CH₂COR₁₁ group, the phenyl group itself being unsubstituted or substituted one or more times with a substituent, each chosen independently from a halogen atom, or a (C₁-C₄)alkyl, trifluoromethyl, hydroxyl, (C₁-C₄)alkoxyl or cyano group;

or a homopiperidin-1-yl, piperidin-1-yl, pyrrolidin-1-yl or azetidin-1-yl radical, said radicals being unsubstituted or substituted once or twice with a substituent, each independently chosen from:

a fluorine atom, or a cyano, —COR₁₁, —NR₁₂R₁₃, —NHCOR₁₄, —CH₂COR₁₁, —SO₂R₁₄, or —SO₂NR₁₂R₁₃ group;

or a phenyl group or a pyridinyl group; said groups being unsubstituted or substituted one or more times with a substituent, each chosen independently from a halogen atom, or a (C₁-C₄)alkyl, trifluoromethyl, hydroxyl, (C₁-C₄)alkoxyl or cyano group;

or a benzyl group which is unsubstituted or substituted one or more times with a substituent, each chosen independently from a halogen atom, or a (C₁-C₄)alkyl, trifluoromethyl, hydroxyl, (C₁-C₄)alkoxyl or cyano group;

or a piperidin-1-yl, pyrrolidin-1-yl or azetidin-1-yl group, said groups being unsubstituted or substituted one or more times with a substituent, each chosen independently from a fluorine atom, or a (C₁-C₄)alkyl, (C₁-C₄)alkoxyl, hydroxyl, trifluoromethyl or OCF₃ group;

or an aminophenyl or aminobenzyl group, said groups being unsubstituted or substituted one or more times with a substituent, each chosen independently from a halogen atom, or a (C₁-C₄)alkyl, trifluoromethyl, hydroxyl, (C₁-C₄)alkoxyl or cyano group;

or an amino(C₁-C₆)alkyl group which is unsubstituted or substituted one or more times with a substituent, each chosen independently from a halogen atom, a hydroxyl group, a (C₁-C₄)alkoxyl group or a cyano group;

or an amino(C₃-C₇)cycloalkyl group which is unsubstituted or substituted one or more times with a substituent, each chosen independently from a halogen atom, a hydroxyl group, a (C₁-C₄)alkyl group, a (C₁-C₄)alkoxyl group or a cyano group, said (C₁-C₄)alkyl group being unsubstituted or substituted one or more times with a fluorine atom;

R₃, R₄, R₅, R₆, R₇, R₈ each independently represent a hydrogen atom, a halogen atom, a —CN, —S(O)_nR₁₄ or —OSO₂R₁₄ group, or a (C₁-C₆)alkyl group which is unsubstituted or substituted one or more times with a fluorine atom or a (C₁-C₆)alkoxyl group which is unsubstituted or substituted with one or more fluorine atoms, on the condition that one of the two substituents R₃ and R₆ represents a Y-A-R₉ group;

Y represents an oxygen atom;

A represents a (C₁-C₄) alkylene group which is unsubstituted or substituted one or more times with a substituent, each chosen independently from a (C₁-C₃)alkyl group or with a fluorine atom;

R₉ represents an —OR₁₂, —CN, —CO₂H, NR₁₂R₁₃, —CONR₁₂R₁₃, —NR₁₅COR₁₂, —CONHNH₂, —CONHOH, —CONHSO₂R₁₄, —S(O)₉R₁₄, —SO₂NR₁₂R₁₃, —NR₁₈SO₂R₁₄ or —NR₁₅SO₂NR₁₂R₁₃;

R₁₀ represents a hydrogen or a (C₁-C₄)alkyl group;

R₁₁ represents:

a (C₁-C₄)alkyl, phenyl, benzyl, (C₁-C₄)alkoxyl or (C₁-C₃)alkylene-O—(C₁-C₃)alkyl group, said groups being unsubstituted or substituted with one or more substituents, each chosen independently from a (C₁-C₄)alkoxyl group, a hydroxyl group or a fluorine atom;

a trifluoromethyl;

or an —NR₁₆R₁₇ group;

R₁₂ and R₁₃ each independently represent a hydrogen atom or a (C₁-C₆)alkyl group optionally substituted with one or more substituents, each chosen independently from a fluorine atom, —OH or —OR₁₄,

or R₁₂ and R₁₃, together with the nitrogen atom to which they are attached, constitute a 4- to 7-membered heterocyclic radical which may comprise a second heteroatom chosen from a nitrogen, oxygen or sulphur atom;

n represents 0, 1 or 2;

R₁₄ represents a (C₁-C₄)alkyl group which is unsubstituted or substituted with one or more fluorine atoms;

R₁₅ represents a hydrogen atom or a (C₁-C₄)alkyl group;

R₁₆ and R₁₇ each independently represent:

a hydrogen atom;

or a benzyl group which is unsubstituted or substituted one or more times with a substituent, each chosen independently from a halogen atom, or a (C₁-C₄)alkyl, trifluoromethyl, hydroxyl, (C₁-C₄)alkoxyl or cyano group;

or a (C₁-C₆)alkyl group optionally substituted with one or more substituents, each chosen independently from a halogen atom, —OH or —OR₁₄;

R₁₈ represents a hydrogen atom or a (C₁-C₄)alkyl group which is unsubstituted or substituted with one or more fluorine atoms;

Alk represents a (C₁-C₄)alkyl group;

or the salt thereof.