US 7,498,355 B2
Derivatives of 4- or 5-aminosalicylic acid
John L. Wallace, Calgary (Canada); Giuseppe Cirino, Naples (Italy); Giuseppe Caliendo, Naples (Italy); Anna Sparatore, Milan (Italy); Vincenzo Santagada, Cosenza (Italy); and Stefano Fiorucci, Perugia (Italy)
Assigned to Antibe Therapeutics Inc., Calgary (Canada)
Filed on Mar. 31, 2006, as Appl. No. 11/278,395.
Application 11/278395 is a continuation in part of application No. 11/139871, filed on May 27, 2005, abandoned.
Prior Publication US 2007/0197479 A1, Aug. 23, 2007
Int. Cl. A61K 31/381 (2006.01); C07D 339/04 (2006.01)
U.S. Cl. 514—441  [549/36] 8 Claims
 
1. A compound of general formula:
A-L-R  (I)
where:

OG Complex Work Unit Drawing
where —NH2 is either at position 4 or 5;
L is either O , O—C═O, S, N or a covalent bond, to form an ester linkage, an anhydride linkage, a thioester linkage, an amide linkage or an acyl linkage; and

OG Complex Work Unit Drawing
or a pharmacologically acceptable salt thereof.