US 7,498,021 B2
Dental products comprising bone growth enhancing peptide
Toshiyuki Yoneda, San Antonio, Tex. (US); Motoyoshi Nomizu, Tokyo (Japan); Yoshinari Kumagai, Hayward, Calif. (US); and Russell Wayne Blacher, Hayward, Calif. (US)
Assigned to Acologix, Inc., Hayward, Calif. (US)
Filed on Apr. 19, 2006, as Appl. No. 11/379,316.
Application 11/379316 is a continuation of application No. 10/344046, granted, now 7,078,021, filed on Jul. 18, 2006, previously published as PCT/US01/25101, filed on Aug. 09, 2001.
Claims priority of provisional application 60/225879, filed on Aug. 16, 2000.
Prior Publication US 2006/0210493 A1, Sep. 21, 2006
This patent is subject to a terminal disclaimer.
Int. Cl. A61K 7/16 (2006.01); A61K 38/00 (2006.01); C07K 17/00 (2006.01)
U.S. Cl. 424—49  [424/50; 530/324; 530/326; 530/328; 530/350; 514/2; 514/7; 514/8; 514/12; 514/14; 514/899; 514/901] 3 Claims
 
1. A formulation, comprising: a pharmaceutically acceptable carrier; and an L-conformation peptide contiguous with an RGD sequence of naturally occurring protein matrix extracellular phosphoglycoprotein consisting of 15 to 35 amino acids, wherein the peptide is comprised of an RGD integrin binding motif and wherein the peptide enhances bone growth.