US 7,491,924 B2
Combination reader
Mark F. Oldham, Los Gatos, Calif. (US); Howard G. King, Berkeley, Calif. (US); Douwe D. Haga, Redwood City, Calif. (US); and Tracy L. Ferea, Mountain View, Calif. (US)
Assigned to Applera Corporation, Foster City, Calif. (US)
Filed on Jul. 23, 2007, as Appl. No. 11/781,515.
Application 11/580100 is a division of application No. 11/188243, filed on Jul. 22, 2005, granted, now 7,135,667.
Application 11/188243 is a division of application No. 10/384995, filed on Mar. 10, 2003, granted, now 6,970,240.
Application 11/781515 is a continuation of application No. 11/580100, filed on Oct. 12, 2006, abandoned.
Prior Publication US 2007/0263209 A1, Nov. 15, 2007
This patent is subject to a terminal disclaimer.
Int. Cl. G01N 21/86 (2006.01); G01T 1/20 (2006.01); G01V 8/00 (2006.01); H01L 27/00 (2006.01)
U.S. Cl. 250—208.1  [250/559.4; 250/361 R; 356/417] 21 Claims
OG exemplary drawing
 
1. A method for collecting images of signals using an imaging apparatus, the method comprising:
placing a sample tile on a stage of the imaging apparatus, the sample tile having an array including a plurality of features, at least a portion of the features each having a hybridized sample;
introducing a first excitation energy upon an area of the sample tile, flooding an entirety of the area of the sample tile with the first excitation energy, and causing a first signal to be emitted;
collecting a first image of at least a portion of the array utilizing an image collecting device of the imaging apparatus, the first image being representative of the first signal; and
collecting a second image of at least a portion of the array utilizing the image collecting device of the imaging apparatus, the second image being representative of a second signal, the second signal being different than the first signal.