| US 7,491,305 B2 | ||
| High density electrophoresis device and method | ||
| Timothy M. Woudenberg, Moss Beach, Calif. (US); and Reid B. Kowallis, Burlingame, Calif. (US) | ||
| Assigned to Applied Biosystems Inc., Foster City, Calif. (US) | ||
| Filed on Dec. 08, 2003, as Appl. No. 10/731,420. | ||
| Application 10/731420 is a continuation of application No. 09/616596, filed on Jul. 14, 2000, granted, now 6,660,147. | ||
| Claims priority of provisional application 60/144103, filed on Jul. 16, 1999. | ||
| Prior Publication US 2004/0178074 A1, Sep. 16, 2004 | ||
| This patent is subject to a terminal disclaimer. | ||
| Int. Cl. G01N 27/453 (2006.01) | ||
| U.S. Cl. 204—601 [204/451; 204/605] | 14 Claims |
| 1. An analytical system comprising:
a substrate including:
a central reservoir region,
a plurality of electrophoretic channels in fluid communication with, and emanating substantially radically from, the central
reservoir region, the channels being coplanar with each other, and each channel having (i) a proximal end which is linked
to the central reservoir region, and (ii) a distal end,
a first chamber that is linked by a first passageway in fluid communication with the distal end of a first of the plurality
of eleetrophoretic channels, and
a second chamber that is linked by a second passageway in fluid communication with the distal end of a second of the plurality
of electrophoretic channels;
a mechanism for rotating the substrate about a central axis of rotation that is perpendicular to the plane of the channels;
and
a plurality of electrodes for applying a voltage potential between the first chamber and the central reservoir region and
between the second chamber and the central reservoir region.
|