US 7,491,243 B2
	Method of modifying a lower esophagus
Dean A. Klein, North Oaks, Minn. (US)
Assigned to Carbon Medical Technologies, St. Paul, Minn. (US)
Filed on Oct. 25, 2002, as Appl. No. 10/280,163.
Application 10/280163 is a continuation in part of application No. 10/084240, filed on Feb. 27, 2002, abandoned.
Prior Publication US 2003/0161887 A1, Aug. 28, 2003
Int. Cl. A61F 2/02 (2006.01)

U.S. Cl. 623—23.68  [623/14.13; 623/23.73]

20 Claims

1. A method of modifying a lower esophagus of a patient comprising injecting an effective amount of a modifier comprising biocompatible carbon coated particles having an average transverse cross-section dimension of between about 80 and about 300 microns and a biocompatible carrier into a plurality of discrete tissue sites within the submucosal layer of the esophagus in the vicinity of a lower esophageal sphincter of the patient.