US 7,491,170 B2
Noninvasive methods for assessing valvular and ventricular dysfunction
Morteza Gharib, San Marino, Calif. (US)
Assigned to California Institute of Technology, Pasadena, Calif. (US)
Filed on Jul. 08, 2003, as Appl. No. 10/615,884.
Claims priority of provisional application 60/459074, filed on Mar. 31, 2003.
Prior Publication US 2004/0193035 A1, Sep. 30, 2004
Int. Cl. A61B 8/00 (2006.01)
U.S. Cl. 600—438 14 Claims
OG exemplary drawing
 
1. A method for assessing progress of valvular dysfunction of a patient comprising:
determining flow parameters of a patient's valve using non-invasive techniques, said flow parameters consisting of an amount of flow over time in an annulus, a diastolic filling period and information indicative of a size of said annulus;
using only said flow parameters to determine a Formation number indicative of cardiac information including information about said annulus, where said Formation number is a non-dimensional parameter;
providing a baseline data of Formation number (Fn) from said patient;
measuring a patient's Fn over time; and
comparing the measured Fn to said baseline data so as to obtain a differential Fn; and
using the differential Fn as an assessment of a progress of the valvular dysfunction.