| US 8,367,643 B2 | ||
| Surfactant lipids, compositions thereof and uses thereof | ||
| Dennis R. Voelker, Greenwood Village, Colo. (US) | ||
| Assigned to National Jewish Health, Denver, Colo. (US) | ||
| Filed by Dennis R. Voelker, Greenwood Village, Colo. (US) | ||
| Filed on Mar. 28, 2008, as Appl. No. 12/57,967. | ||
| Claims priority of provisional application 61/025,298, filed on Jan. 31, 2008. | ||
| Claims priority of provisional application 60/908,837, filed on Mar. 29, 2007. | ||
| Prior Publication US 2008/0242640 A1, Oct. 2, 2008 | ||
| Int. Cl. A61K 35/00 (2006.01); A61K 39/395 (2006.01) | ||
| U.S. Cl. 514—120 | 14 Claims |
| 1. A method to inhibit influenza infection or inflammation associated with influenza infection, comprising administering to
an individual who has, or is at risk of developing said infection or inflammation, an amount of a pure preparation of a phosphatidylglycerol,
wherein the amount of the phosphatidylglycerol is effective to inhibit said infection or inflammation, and wherein the phosphatidylglycerol
has the following characteristics:
a) has a hydrophobic portion;
b) has a negatively charged portion; and
c) has an uncharged, polar portion.
|