| US 7,488,935 B2 | ||
| Apparatus and method for processing of mass spectrometry data | ||
| Lee H. Altmayer, Wilmington, Del. (US) | ||
| Assigned to Agilent Technologies, Inc., Santa Clara, Calif. (US) | ||
| Filed on Jun. 24, 2005, as Appl. No. 11/165,871. | ||
| Prior Publication US 2007/0023642 A1, Feb. 01, 2007 | ||
| Int. Cl. B01D 59/44 (2006.01) | ||
| U.S. Cl. 250—281 [250/282] | 19 Claims |
| 1. A mass spectrometry system, comprising:
(a) an ion source to ionize a sample stream;
(b) a detector positioned downstream with respect to the ion source to acquire mass spectrometry data of the sample stream;
and
(c) a data analyzer connected to the detector and comprising:
(i) a chromatogram generator to process the mass spectrometry data to derive a chromatogram that includes a sequence of data
points arranged based on scan number;
(ii) a data point selector to reorder the sequence of data points according to magnitudes of the sequence of data points to
thereby generate a reordered sequence of data points and to apply a selection criterion to the reordered sequence of data
points to select data points from the chromatogram; and
(iii) a peak discriminator to apply a matched filter to the data points to detect a peak in the chromatogram, wherein a width
of the matched filter is defined based on an expected width of the peak, and the peak is indicative of a presence of an analyte
in the sample stream.
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