US 7,488,706 B2
Alkylamine as an antimicrobial agent in ophthalmic compositions
Zhi-Jian Yu, Irvine, Calif. (US)
Assigned to Advanced Medical Optics, Inc., Santa Ana, Calif. (US)
Filed on Sep. 25, 2006, as Appl. No. 11/534,990.
Application 11/534990 is a division of application No. 10/820354, filed on Apr. 07, 2004, granted, now 7,157,412.
Prior Publication US 2008/0125494 A1, May 29, 2008
Int. Cl. C11D 1/72 (2006.01); C11D 1/722 (2006.01); C11D 3/26 (2006.01); C11D 3/48 (2006.01)
U.S. Cl. 510—112  [510/383; 510/384; 510/391; 510/506; 510/499; 510/504; 514/839; 514/840] 10 Claims
 
1. A method for maintaining ocular tissue cell membrane integrity during contact lens wear comprising:
contacting the lens with an aqueous solution comprising from about 0.1 to about 10 ppm of a primary, secondary, or tertiary alkylamine having the following formula

OG Complex Work Unit Drawing
where R1 is a C13-17 alkyl, and R2 and R3 are each independently H or —CH3; and
a non-ionic surfactant in an amount effective to render the alkylamine soluble in the aqueous solution.