US 7,488,587 B2
	Histone deacetylase and methods of use thereof
Eric Verdin, San Francisco, Calif. (US); Wolfgang Fischle, Charlottesville, Va. (US); and Franck O. Dequiedt, San Francisco, Calif. (US)
Assigned to The J. David Gladstone Institutes, San Francisco, Calif. (US)
Filed on Jun. 17, 2002, as Appl. No. 10/175,559.
Claims priority of provisional application 60/299228, filed on Jun. 19, 2001.
Prior Publication US 2003/0143712 A1, Jul. 31, 2003
Int. Cl. C07H 21/00 (2006.01); C07H 21/02 (2006.01)

U.S. Cl. 435—69.1  [536/23.1]

12 Claims

1. An isolated nucleic acid molecule comprising a nucleotide sequence encoding an enzymatically active histone deacetylase-7 (HDAC-7) polypeptide, wherein said HDAC-7-encoding nucleotide sequence has at least 95% nucleotide sequence identity to the coding region of SEQ ID NO:1, wherein the encoded HDAC-7 polypeptide comprises an amino acid sequence having at least 95% sequence identity to the amino acid sequence set forth in SEQ ID NO:2.