| US 7,486,865 B2 | ||
| Substrates for performing analytical reactions | ||
| Mathieu Foquet, Redwood City, Calif. (US); Paul Peluso, Hayward, Calif. (US); Stephen Turner, Menlo Park, Calif. (US); Daniel Bernardo Roitman, Menlo Park, Calif. (US); and Geoffrey Otto, Santa Clara, Calif. (US) | ||
| Assigned to Pacific Biosciences of California, Inc., Menlo Park, Calif. (US) | ||
| Filed on Jun. 11, 2007, as Appl. No. 11/761,251. | ||
| Claims priority of provisional application 60/812863, filed on Jun. 12, 2006. | ||
| Prior Publication US 2008/0095488 A1, Apr. 24, 2008 | ||
| Int. Cl. G02B 6/10 (2006.01) | ||
| U.S. Cl. 385—129 [385/130; 385/131] | 30 Claims |

| 1. A zero mode waveguide substrate, comprising:
a transparent substrate layer having at least a first surface;
a metal cladding layer disposed upon the first surface of the transparent substrate layer;
an aperture disposed through the cladding layer to the transparent substrate layer, and forming a core region surrounded by
the metal cladding layer, wherein the core is dimensioned to prevent electromagnetic radiation of a frequency greater than
a cut-off frequency from propagating entirely through the core; and
a sacrificial anode disposed upon the cladding layer.
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