US 7,486,865 B2
Substrates for performing analytical reactions
Mathieu Foquet, Redwood City, Calif. (US); Paul Peluso, Hayward, Calif. (US); Stephen Turner, Menlo Park, Calif. (US); Daniel Bernardo Roitman, Menlo Park, Calif. (US); and Geoffrey Otto, Santa Clara, Calif. (US)
Assigned to Pacific Biosciences of California, Inc., Menlo Park, Calif. (US)
Filed on Jun. 11, 2007, as Appl. No. 11/761,251.
Claims priority of provisional application 60/812863, filed on Jun. 12, 2006.
Prior Publication US 2008/0095488 A1, Apr. 24, 2008
Int. Cl. G02B 6/10 (2006.01)
U.S. Cl. 385—129  [385/130; 385/131] 30 Claims
OG exemplary drawing
 
1. A zero mode waveguide substrate, comprising:
a transparent substrate layer having at least a first surface;
a metal cladding layer disposed upon the first surface of the transparent substrate layer;
an aperture disposed through the cladding layer to the transparent substrate layer, and forming a core region surrounded by the metal cladding layer, wherein the core is dimensioned to prevent electromagnetic radiation of a frequency greater than a cut-off frequency from propagating entirely through the core; and
a sacrificial anode disposed upon the cladding layer.