US 7,485,750 B2
Hydroxamic acid derivatives and the preparation method thereof
Ho Sik Rho, Yongin-si (Korea, Republic of); Heung Soo Baek, Anyang-si (Korea, Republic of); Jeong A. Lee, Yongin-si (Korea, Republic of); Chang Man Park, Seoul (Korea, Republic of); Duck Hoo Kim, Seoul (Korea, Republic of); Ih Soop Chang, Yongin-si (Korea, Republic of); and Ok Sub Lee, Anyang-si (Korea, Republic of)
Assigned to Amorepacific Corporation, Seoul (Korea, Republic of)
Appl. No. 11/919,131
PCT Filed Mar. 21, 2006, PCT No. PCT/KR2006/001019
§ 371(c)(1), (2), (4) Date Dec. 17, 2007,
PCT Pub. No. WO2006/118380, PCT Pub. Date Nov. 09, 2006.
Claims priority of application No. 10-2005-0035986 (KR), filed on Apr. 29, 2005.
Prior Publication US 2008/0242730 A1, Oct. 02, 2008
Int. Cl. C07C 259/04 (2006.01); A61K 31/19 (2006.01)
U.S. Cl. 562—621  [562/622; 514/575] 6 Claims
 
1. A hydroxamic acid derivative represented by the following formula (1):

OG Complex Work Unit Drawing
wherein,
R1 and R2 are an alkyl group having from 1 to 10 carbon atoms;
R3 is —(CH)n—, wherein n=0 or 1; and
R4 is a hydrogen atom or methyl.