US 7,485,699 B2
	Cytokine protein family
Paul O. Sheppard, Granite Falls, Wash. (US); Brian A. Fox, Seattle, Wash. (US); Kevin M. Klucher, Bellevue, Wash. (US); David W. Taft, Kirkland, Wash. (US); and Wayne Kindsvogel, Seattle, Wash. (US)
Assigned to ZymoGenetics, Inc., Seattle, Wash. (US)
Filed on Oct. 05, 2006, as Appl. No. 11/539,043.
Application 11/539043 is a division of application No. 11/266626, filed on Nov. 03, 2005, abandoned.
Application 11/266626 is a division of application No. 10/127816, filed on Apr. 19, 2002, granted, now 7,038,032.
Application 10/127816 is a continuation in part of application No. 09/895834, filed on Jun. 29, 2001, granted, now 6,927,040.
Claims priority of provisional application 60/285424, filed on Apr. 20, 2001.
Claims priority of provisional application 60/285408, filed on Apr. 20, 2001.
Claims priority of provisional application 60/286482, filed on Apr. 25, 2001.
Claims priority of provisional application 60/341050, filed on Oct. 22, 2001.
Claims priority of provisional application 60/341105, filed on Oct. 22, 2001.
Prior Publication US 2008/0132680 A1, Jun. 05, 2008
This patent is subject to a terminal disclaimer.
Int. Cl. C07K 14/52 (2006.01); C07K 14/00 (2006.01); C12N 15/24 (2006.01)

U.S. Cl. 530—351  [530/350; 530/412; 530/413; 435/69.52; 435/69.7]

11 Claims

1. A fusion protein comprising a polypeptide having at least 95% sequence identity with amino acid residues 22-205 of SEQ ID NO:2 and an affinity tag, wherein the polypeptide binds a receptor as shown in SEQ ID NOs:24, 27 or 29 as a monomeric or homodimeric receptor or a receptor as shown in SEQ ID NOs:24, 27 or 29 in combination with SEQ ID NO:41 as a heterodimeric receptor.