US 7,485,662 B2
	Therapeutic agent for diabetes mellitus
Toshikazu Kamiya, Tsuchiura (Japan); Akio Shirai, Koto-ku (Japan); Miho Takada, Tsukuba (Japan); and Fumiko Ogino, Tsukuba (Japan)
Assigned to Kyowa Hakko Kogyo Co., Ltd., Tokyo (Japan)
Appl. No. 10/549,155 PCT Filed Mar. 19, 2004, PCT No. PCT/JP2004/003763 § 371(c)(1), (2), (4) Date Sep. 15, 2005, PCT Pub. No. WO2004/083179, PCT Pub. Date Sep. 30, 2004.
Claims priority of application No. 2003-074823 (JP), filed on Mar. 19, 2003.
Prior Publication US 2006/0173066 A1, Aug. 03, 2006
Int. Cl. A61K 31/40 (2006.01); A61K 31/21 (2006.01)

U.S. Cl. 514—408  [514/424; 514/506]

1 Claim

1. A method for improving insulin resistance comprising administering, to a patient in need thereof, an effective amount of N-acetylhydroxyproline or N,O-diacetylhydroxyproline oleyl ester.