US 7,482,479 B2
	Production of cis-pellitorin and use as a flavouring
Ian-Lucas Gatfield, Höxter (Germany); Jakob Ley, Holzminden (Germany); Jan Foerstner, Holzminden (Germany); Gerhard Krammer, Holzminden (Germany); and Arnold Machinek, Holzminden (Germany)
Assigned to Symrise GmbH & Co., KG, Holzminden (Germany)
Appl. No. 10/518,074 PCT Filed Jun. 20, 2003, PCT No. PCT/EP03/06545 § 371(c)(1), (2), (4) Date Dec. 16, 2004, PCT Pub. No. WO04/000787, PCT Pub. Date Dec. 31, 2003.
Claims priority of application No. 102 27 462 (DE), filed on Jun. 20, 2002.
Prior Publication US 2005/0234132 A1, Oct. 20, 2005
This patent is subject to a terminal disclaimer.
Int. Cl. C07C 231/00 (2006.01)

U.S. Cl. 554—69  [514/627]

18 Claims

1. Process for the production of 2E,4Z-decadienoic acid-N-isobutylamide (cis-pellitorine), characterised in that a 2E,4Z-decadienoic acid ester is reacted with isobutylamine in the presence of an enzyme catalyst, and then isolating the mixture by physico-chemical methods.