US 7,482,459 B2
[4-(5-aminomethyl-2-fluoro-phenyl)-piperidin-1-yl]-(4-bromo-3-methyl-5-propoxy-thiophen-2-yl)-methanone hydrochloride as an inhibitor of mast cell tryptase
Zhongli Gao, Flemington, N.J. (US); Larry Davis, Sergeantsville, N.J. (US); Julian Levell, Arlington, Mass. (US); Mark Czekaj, Doylestown, N.J. (US); and Adam W. Sledeski, Belle Mead, N.J. (US)
Assigned to Aventis Pharmaceuticals Inc., Bridgewater, N.J. (US)
Filed on Sep. 14, 2006, as Appl. No. 11/520,998.
Application 11/520998 is a continuation of application No. PCT/US2005/009899, filed on Mar. 24, 2005.
Claims priority of provisional application 60/556927, filed on Mar. 26, 2004.
Prior Publication US 2007/0142435 A1, Jun. 21, 2007
Int. Cl. C07D 211/00 (2006.01); C07D 409/00 (2006.01); C07D 405/00 (2006.01)
U.S. Cl. 546—188  [546/212; 546/214] 4 Claims
 
1. A compound of formula I:

OG Complex Work Unit Drawing
or a pharmaceutically acceptable salt thereof.