US 7,482,381 B2
	Artificial muscle hydrogel blends reversibly electroactuated near neutral pH, implantable actuating devices, and methods using the same
Sylvia Daunert, 4804 Pleasant Lawn Way, Lexington, Ky. 40515 (US); Serban F. Peteu, 802 Cherry La., Apartment 106, East Lansing, Mich. 48823-5543 (US); Leonidas G. Bachas, 4804 Pleasant Lawn Way, Lexington, Ky. 40515 (US); Marc J. Madou, 10390 Pacific Center Ct., San Diego, Calif. 92121 (US); and Elissavet Moschou, 3051 Kirklevington Dr., Apt. 66, Lextington, Ky. 40517 (US)
Filed on Mar. 19, 2004, as Appl. No. 10/803,985.
Claims priority of provisional application 60/509054, filed on Mar. 19, 2003.
Prior Publication US 2004/0182704 A1, Sep. 23, 2004
Int. Cl. A61K 47/30 (2006.01); A61K 47/00 (2006.01); A61K 9/14 (2006.01); A61F 13/00 (2006.01)

U.S. Cl. 514—772.3  [514/784; 424/422; 424/487]

17 Claims

1. An electroactive hydrogel composition comprising acrylamide; unsaturated aliphatic acid having the formula R═CH—COOH, wherein R is selected from the group consisting of —CH2, —CH—COOH, and —CH—(CH2)n—COOH, where n is an integer, or a combination of these aliphatic acids; a conductive polymer; and at least one cross-linking agent, wherein the hydrogel is electroactive in the absence of contact with electrodes and at a pH range of from about 3 to about 10.