or a stereoisomer or a pharmaceutically acceptable salt thereof, wherein:

ring B is a cyclohexyl group wherein the cyclohexyl group is substituted with 1-2 R⁵;

X is selected from O or S;

Z is selected from —NR⁸C(O)—, —NR⁸C(S)—, —NR⁸C(O)NH—, —NR⁸C(S)NH—, —NR⁸SO₂—, —NR⁸SO₂NH—, —C(O)NR⁸—, —OC(O)NR⁸—, —NR⁸C(O)O—, —CR¹⁴═CR¹⁴—, —CR¹⁵R¹⁵—, —CR¹⁵R¹⁵C(O)—, —C(O)CR¹⁵R¹⁵—, —CR¹⁵R¹⁵C(═N—OR¹⁶)—, —O—CR¹⁴R¹⁴—, —CR¹⁴R¹⁴—O—, —O—, —NR⁹—, —NR⁹—CR¹⁴R¹⁴—, —CR¹⁴R¹⁴—NR⁹—, —S(O)_p—, —S(O)_p—CR¹⁴ R¹⁴, —CR¹⁴R¹⁴—S(O)_p—, and —S(O)_p—NR⁹—;

wherein neither Z nor R¹³ are connected to a carbon atom labeled (b);

bond (a) is a single bond or double bond;

R¹ is selected from H, R⁶, C_1-6 alkyl substituted with 0-3 R⁶, C_2-6 alkenyl substituted with 0-3 R⁶, C_2-6 alkynyl substituted with 0-3 R⁶, C_6-10 aryl group substituted with 0-5 R⁶, wherein the aryl group is selected from phenyl and napthyl, and a 5-10 membered heteroaryl system containing 1-4 heteroatoms selected from N, O, and S, substituted with 0-3 R⁶, wherein the heteroaryl is selected from indolyl, benzimidazolyl, benzofuranyl, benzothiofuranyl, benzoxazolyl, benzthiazolyl, benztriazolyl, benztetrazolyl, benzisoxazolyl, benzisothiazolyl, benzimidazalonyl, cinnolinyl, furanyl, imidazolyl, indazolyl, indolyl, isonicotinyl, isoquinolinyl isothiazolyl, isoxazolinyl, isoxazolyl, oxazolyl, phthalazinyl, picolinyl, pyrazinyl, pyrazolyl, pyridazinyl, pyridyl, pyridinyl, pyrimidinyl, pyrrolyl, quinazolinyl, quinolinyl, thiazolyl, thienyl, triazinyl, and tetrazolyl; with the proviso that if R¹ is H, then R⁵ is (CH₂)_rNR^5aR^5a; and with the further proviso that if R⁵ is H, then R¹ is not H or methyl;

R² is selected from phenyl substituted with 0-2 R⁷, and a 5-10 membered heteroaryl system containing 1-4 heteroatoms selected from N, O, and S, substituted with 0-3 R⁷ wherein the heteroaryl is selected from indolyl, benzimidazolyl, benzofuranyl, benzothiofuranyl, benzoxazolyl, benzthiazolyl, benztriazolyl, benztetrazolyl, benzisoxazolyl, benzisothiazolyl, benzimidazalonyl, cinnolinyl, furanyl, imidazolyl, indazolyl, indolyl, isoquinolinyl isothiazolyl, isoxazolyl, oxazolyl, phthalazinyl, pyrazinyl, pyrazolyl, pyridazinyl, pyridyl, pyridinyl, pyrimidinyl, pyrrolyl, pyrrolotriazinyl, quinazolinyl, quinolinyl, thiazolyl, thienyl, and tetrazolyl;

R⁵, at each occurrence, is independently selected from H, methyl, ethyl, propyl, i-propyl, butyl, i-butyl, allyl, propynyl, F, Cl, Br, I, (CH₂)_rOH, (CH₂)_rOR^5d, (CH₂)_rNR^5aR^5a, (CH₂)_rC(O)R^5b, (CH₂)_rC(O)NR^5aR^5a, (CH₂)_rNR^5aC(O)R^5b, (CH₂)_rOC(O)NR^5aR^5a, (CH₂)_rNR^5aC(O)OR^5d, (CH₂)_rNR^5aC(O)R^5b, (CH₂)_rC(O)OR^5b, (CH₂)_rOC(O)R^5b, (CH₂)_rNR^5aS(O)₂R^5b, and C_1-6 haloalkyl, (CH₂)_rphenyl substituted with 0-2 R^5e, and a (CRR)_r-5-10 membered heterocyclic system containing 1-4 heteroatoms selected from N, O, and S, substituted with 0-2 R^5c, wherein the heterocyclic system is selected from pyrrolidinyl, piperidinyl, and morpholinlyl;

R^5a, at each occurrence, is independently selected from H, methyl, ethyl, propyl, i-propyl, butyl, i-butyl, pentyl, hexyl, cyclopropyl, and cyclobutyl;

R^5b, at each occurrence, is selected from C_1-6 alkyl substituted with 0-3 R^5e, C_1-6 haloalkyl, C_3-8 alkenyl substituted with 0-2 R^5e, C_3-8 alkynyl substituted with 0-2 R^5e, a (CH₂)_r—C_3-6 carbocyclic residue substituted with 0-2 R^5e, and a (CH₂)_r-5-6 membered heterocyclic system containing 1-4 heteroatoms selected from N, O, and S, substituted with 0-3 R^5e;

R^5c, at each occurrence, is selected from C_1-6 alkyl, C_2-8 alkenyl, C_2-8 alkynyl, (CH₂)_rC_3-6 cycloalkyl, Cl, Br, I, F, (CF₂)_rCF₃, NO₂, CN, (CH₂)_rNR^5fR^5f, (CH₂)_rOH, (CH₂)_rOC_1-4 alkyl, (CH₂)_rSC_1-4 alkyl, (CH₂)_rC(O)OH, (CH₂)_rC(O)R^5b, (CH₂)_rC(O)NR^5fR^5f, (CH₂)rOC(O)NR^5fR^5f, (CH₂)_rNR^5fC(O)R^5b, (CH₂)_rC(O)OC_1-4 alkyl, (CH₂)_rNR^5fC(O)OC_1-4 alkyl, (CH₂)_rOC(O)R^5b, (CH₂)_rC(═NR^5f)NR^5fR^5f, (CH₂)_rS(O)_pR^5b, (CH₂)_rNHC(═NR^5f)NR^5fR^5f, (CH₂)_rS(O)₂NR^5fR^5f, (CH₂)_rNR^5fS(O)₂R^5b, C(O)OH, (CH₂)_rC(O)NHSO₂R^5h, NHSO₂—R^5h, (CH₂)_rtetrazolyl, and (CH₂)_rphenyl substituted with 0-3 R^5e;

R^5d, at each occurrence, is selected from methyl, CF₃, C_2-6 alkyl substituted with 0-2 R^5e, C_3-8 alkenyl substituted with 0-2 R^5e, C_3-8 alkynyl substituted with 0-2 R^5e, and a C_3-10 carbocyclic residue substituted with 0-3 R^5e;

R^5e, at each occurrence, is selected from C_1-6 alkyl, C_2-8 alkenyl, C_2-8 alkynyl, C_3-6 cycloalkyl, Cl, F, Br, I, CN, NO₂, (CF₂)_rCF₃, (CH₂)_rOC_1-5 alkyl, OH, SH, (CH₂)_rSC_1-5 alkyl, (CH₂)_rNR^5fR^5f, (CH₂)_rC(O)NHR^5h, (CH₂)_rOC(O)NHR^5h, (CH₂)_rOH, (CH₂)_rC(O)OH, (CH₂)_rC(O)NHSO₂—R^5h, NHSO₂R^5h, a (CH₂)_r-5-6 membered heterocyclic system containing 1-4 heteroatoms selected from N, O, and S, and (CH₂)_rphenyl;

R^5f, at each occurrence, is selected from H, C_1-6 alkyl, and C_3-6 cycloalkyl;

R^5h, at each occurrence, is selected from C_1-5 alkyl, C_1-5 haloalkyl, and C_3-6 cycloatkyl, and phenyl;

R, at each occurrence, is independently selected from H, methyl, ethyl, propyl, allyl, propynyl, (CH₂)_rC_3-6 cycloalkyl, and (CH₂)_rphenyl substituted with R^5e;

R⁶, at each occurrence, is selected from C_1-8 alkyl, C_2-8 alkenyl, C_2-8 alkynyl, (CH₂)_rC_3-6 cycloalkyl, Cl, Br, I, F, NO₂, CN, (CH₂)_rNR^6a′R^6a′, (CH₂)_rOH, (CH₂)_rO(CH₂)_rR^6d, (CH₂)_rSH, (CH₂)_rC(O)H, (CH₂)_rS(CH₂)_rR^6d, (CH₂)_rC(O)OH, (CH₂)_rC(O)(CH₂)_rR^6b, (CH₂)_rC(O)NR^6aR^6a, (CH₂)_rNR^6fC(O)R^6b′, (CH₂)_rNR^6aC(O)NR^6a′R^6d′, (CH₂)_rNR^6aC(S)NR^6aR^6a, (CH₂)_rOC(O)(CH₂)_rR^6b, (CH₂)_rS(O)_pR^6b′, (CH₂)_rS(O)₂NR^6aR^6a, (CH₂)_rNR^6fS(O)₂(CH₂)_rR^6b, (CH₂)_rNR^6fS(O)₂NR^6aR^6a, C_1-6 haloalkyl, (CH₂)_rphenyl substituted with 0-3 R^6e, and a (CH₂)_r-5-6 membered heterocyclic system containing 1-2 heteroatoms selected from N, O, and S, substituted with 0-2 R^6e, wherein the heterocyclic system is selected from aziridinyl, azetidinyl, pyrrolyl, piperidinyl, and morpholinyl;

R^6a, at each occurrence, is independently selected from H, methyl, ethyl, propyl, i-propyl, butyl, i-butyl, t-butyl, pentyl, hexyl, cyclopropyl and phenyl;

R^6a′, at each occurrence, is selected from H, C_1-6 alkyl and C_3-6 cycloalkyl;

R^6b, at each occurrence, is selected from H, methyl, ethyl, propyl, i-propyl, butyl, i-butyl, t-butyl, pentyl, hexyl, cyclopropyl, and phenyl;

R^6b′, at each occurrence, is selected from H, C_1-6 alkyl and C_3-6 cycloalkyl;

R^6d, at each occurrence, is selected from methyl, CF₃, ethyl, propyl, i-propyl, butyl, i-butyl, t-butyl, pentyl, hexyl, cyclopropyl, and phenyl;

R^6d′, at each occurrence, is selected from H, CF₃ and C_1-6 alkyl and C_3-6 cycloalkyl;

R^6e, at each occurrence, is selected from C_1-6 alkyl, C_2-8 alkenyl, C_2-8 alkynyl, (CH₂)_rC_3-6 cycloalkyl, Cl, F, Br, I, CN, NO₂, (CF₂)_rCF₃, (CH₂)_rOC_1-5 alkyl, OH, SH, (CH₂)_rSC_1-5 alkyl, (CH₂)_rNR^6fR^6f, C(O)NHR^6h, C(O)OC_1-5 alkyl, (CH₂)_rOH, C(O)OH, (CH₂)_rC(O)NHSO₂—R^6h, NHSO₂R^6h, (CH₂)_rtetrazolyl, (CH₂)_rphenyl and a (CH₂)_r-5-6 membered heterocyclic system containing 1-4 heteroatoms selected from N, O, and S;

R^6f, at each occurrence, is selected from H, methyl, ethyl, propyl, i-propyl, butyl, i-butyl, t-butyl, pentyl, hexyl, cyclopropyl, and phenyl;

R^6h, at each occurrence, is selected from C_1-5 alkyl, C_1-5 haloalkyl, and C_3-6 cycloalkyl, and phenyl;

R⁷ is selected from methyl, ethyl, propyl, i-propyl, butyl, i-butyl, s-butyl, t-butyl, pentyl, hexyl, (CH₂)_rC_3-6 cycloalkyl, Cl, Br, I, F, NO₂, CN, (CH₂)_rNR^7aR^7a, (CH₂)_rOH, (CH₂)_rO(CH₂)_rR^7d, (CH₂)_rSH, (CH₂)_rC(O)H, (CH₂)_rS(CH₂)_rR^7d, (CH₂)_rC(O)OH, (CH₂)_rC(O)(CH₂)_rR^7b, (CH₂)_rC(O)NR^7aR^7a, (CH₂)_rNR^7fC(O)(CH₂)_rR^7b, (CH₂)_rC(O)O(CH₂)_rR^7d, (CH₂)_rOC(O)(CH₂)_rR^7b, (CH₂)_rOC(O)NR^7aR^7a, (CH₂)_rNR^7aC(O)NR^7aR^7a, (CH₂)_rNR^7aC(O)O(CH₂)_rR^7d, (CH₂)_rS(O)_p(CH₂)_rR^7b, (CH₂)_rS(O)₂NR^7aR^7a, (CH₂)_rNR^7fS(O)₂(CH₂)_rR^7b, C_1-6 haloatkyl, adamantyl, (CH₂)_rphenyl substituted with 0-3 R^7e, and a (CH₂)_r-5-6 membered heterocyclic system containing 1-4 heteroatoms selected from N, O, and S, substituted with 0-3 R^7e, wherein the heterocyclic system is selected from thienyl, pyridinyl, benzothiazolyl, and tetrazolyl;

R^7a, at each occurrence, is selected from H, methyl, ethyl, propyl, i-propyl, butyl, i-butyl, t-butyl, pentyl, hexyl, prop-2-enyl, 2-methyl-2-propenyl, cyclopropyl, cyclobutyl, cyclopentyl, cyclohexyl, CH₂cyclopropyl, and benzyl;

R^7b, at each occurrence, is selected from methyl, ethyl, propyl, i-propyl, butyl, i-butyl, t-butyl, pentyl, hexyl, cyclopropyl, cyclopentyl, CH₂-cyclopentyl, cyclohexyl, CH₂-cyclohexyl, CF₃, pyrrolidinyl, morpholinyl, piperazinyl, piperidinyl, substituted with 0-1 R^7e, and azetidinyl;

R^7d, at each occurrence, is selected from methyl, CF₃, CF₂CF₃, CHF₂, CH₂F, ethyl, propyl, i-propyl, butyl, i-butyl, t-butyl, pentyl, hexyl, and cyclopropyl;

R^7e, at each occurrence, is selected from C_1-6 alkyl, C_2-8 alkenyl, C_2-8 alkynyl, (CH₂)_rC_3-6 cycloalkyl, Cl, F, Br, I, CN, NO₂, (CF₂)_rCF₃, (CH₂)_rOC_1-5 alkyl, (CH₂)_rOH, OH, SH, C(O)OH, C(O)NHR^7h, C(O)OC_1-5 alkyl, (CH₂)_rSC_1-5 alkyl, (CH₂)_rNR^7fR^7f, (CH₂)_rC(O)NHSO₂—R^7h, NHSO₂R^7h, and (CH₂)_rphenyl, and (CH₂)_rtetrazolyl;

R^7f, at each occurrence, is selected from H, methyl, ethyl, propyl, i-propyl, butyl, i-butyl, t-butyl, pentyl, hexyl, cyclopropyl, and phenyl;

R^7h, at each occurrence, is selected from C_1-5 alkyl, C_1-5 haloalkyl, and C_3-6 cycloalkyl, and phenyl;

R⁸ is selected from H, methyl, ethyl, propyl, i-propyl, and cyclopropyl;

R⁹ is selected from H, C_1-4 alkyl, C_3-4 cycloalkyl, —C(O)H, and —C(O)—C_1-4alkyl;

R¹⁰ is H;

R¹¹ is selected from H, C_1-4 alkyl, (CHR)_qOH, (CHR)_qSH, (CHR)_qOR^11d, (CHR)_qS(O)_pR^11d, (CHR)_rC(O)R^11b, (CHR)_rNR^11aR^11a, (CHR)_rC(O)NR^11aR^11a, (CHR)_rC(O)NR^11aOR^11d, (CHR)_qNR^11aC(O)R^11b, (CHR)_qNR^11aC(O)OR^11d, (CHR)_qOC(O)NR^11aR^11a, (CHR)_rC(O)OR^11d, a (CHR)_r—C_3-6 carbocyclic residue substituted with 0-5 R^11e, and a (CHR)_r-5-10 membered heterocyclic system containing 1-4 heteroatoms selected from N, O, and S, substituted with 0-3 R^11e;

R^11a, at each occurrence, is independently selected from H, C_1-4 alkyl, C_3-4 alkenyl, C_3-4 alkynyl, (CH₂)_rC_3-6 cycloalkyl, and a (CH₂)_r-5-6 membered nonaromatic heterocyclic system containing 1-4 heteroatoms selected from N, O, and S, substituted with 0-3 R^11e;

R^11b, at each occurrence, is independently selected from C_1-4 alkyl, C_2-4 alkenyl, C_2-4 alkynyl, a (CH₂)_r-C_3-6 cycloalkyl substituted with 0-2 R^11e, and a (CH₂)_r-5-6 membered nonaromatic heterocyclic system containing 1-4 heteroatoms selected from N, O, and S, substituted with 0-3 R^11e;

R^11d, at each occurrence, is independently selected from H, methyl, —CF₃, C_2-4 alkyl, C_3-6 alkenyl, C_3-6 alkynyl, a C_3-6 cycloalkyl substituted with 0-3 R^11e, and a (CH₂)_r-5-6 membered nonaromatic heterocyclic system containing 1-4 heteroatoms selected from N, O, and S, substituted with 0-3 R^11e;

R^11e, at each occurrence, is selected from C_1-6 alkyl, C_2-8 alkenyl, C_2-8 alkynyl, C_3-6 cycloalkyl, Cl, F, Br, I, CN, NO₂, (CF₂)_rCF₃, (CH₂)_rOC_1-5 alkyl, OH, —O—C_1-6 alkyl, SH, (CH₂)_rSC_1-5 alkyl, (CH₂)_rNR^11fR^11f, and (CH₂)_rphenyl;

R^11f, at each occurrence, is selected from H, C_1-6 alkyl, and C_3-6 cycloalkyl;

R¹² is selected from H, C_1-4 alkyl, and a (CHR)_r—C_3-6 carbocyclic residue substituted with 0-5 R^l2e;

R^l2e, at each occurrence, is selected from C_1-6 alkyl, C_2-8 alkenyl, C_2-8 alkynyl, C_3-6 cycloalkyl, Cl, F, Br, I, CN, NO₂, (CF₂)_rCF₃, (CH₂)_rOC_1-5 alkyl, OH, —O—C_1-6 alkyl, SH, (CH₂)_rSC_1-5 alkyl, (CH₂)_rNR^12fR^12f, and (CH₂)_rphenyl;

R^12f, at each occurrence, is selected from H, C_1-6 alkyl, and C_3-6 cycloalkyl;

R¹³, at each occurrence, is independently selected from H, and C_1-4 alkyl substituted with 0-1 R^l3b, —OH, —NH₂, F, Cl, Br, I, —OR^13a, —N(R^l3a)₂, and C_1-4 alkyl substituted with 0-3 R^l3b;

R^13a is selected from H, C_1-4 alkyl and C_3-6 cycloalkyl;

R^l3b, at each occurrence, is independently selected from —OH, —SH, —NR^l3cR^l3c, —C(O)NR^l3cR^l3c, and —NHC(O)R^l3c;

R^l3c is selected from H, C_1-4 alkyl and C_3-6 cycloalkyl;

R¹⁴, at each occurrence, is independently selected from H and C_1-4 alkyl;

alternatively, two R¹⁴s, along with the carbon atom to which they are attached, join to form a C_3-6 carbocyclic ring;

R¹⁵, at each occurrence, is independently selected from H, C_1-4alkyl, OH, NH₂, —O—C_1-4 alkyl, NR^15aR^l5a, C(O)NR^15aR^15a, NR^15aC(O)R^15b, NR^15aC(O)OR^15d, OC(O)NR^15aR^15a, and (CHR)_rC(O)OR^15d;

alternatively, two R¹⁵s, along with the carbon atom or atoms to which they are attached, join to form a C_3-6 carbocyclic ring;

R^15a, at each occurrence, is independently seleced from H, and C_1-4 alkyl;

R^15b, at each occurrence, is independently selected from C_1-4 alkyl, C_3-6 alkenyl, and C_3-6 alkynyl;

R^15d, at each occurrence, is independently selected from C_1-4 alkyl, C_3-6 alkenyl, and C_3-6 alkynyl;

R¹⁶ is selected from C_1-4 alkyl;

n is 1;

m is selected from 0 and 1;

p, at each occurrence, is independently selected from 0, 1, and 2;

q, at each occurrence, is independently selected from 1, 2, 3, and 4;

r is 0 or 1; and

s is 0.