US 7,482,173 B2
Method for attachment of silylated molecules to glass surfaces
Viswanadham Garimella, Vernon Hills, Ill. (US); and Yasmith Bernal, Lake Zurich, Ill. (US)
Assigned to Nanosphere, Inc., Northbrook, Ill. (US)
Filed on Jan. 19, 2007, as Appl. No. 11/656,312.
Application 11/656312 is a division of application No. 10/447073, filed on May 28, 2003, granted, now 7,297,553.
Claims priority of provisional application 60/383564, filed on May 28, 2002.
Prior Publication US 2008/0097115 A1, Apr. 24, 2008
Int. Cl. G01N 33/543 (2006.01); G01N 33/551 (2006.01); G01N 33/552 (2006.01); G01N 33/00 (2006.01); C12Q 1/00 (2006.01); C12Q 1/68 (2006.01); C12N 11/00 (2006.01)
U.S. Cl. 436—518  [436/524; 436/527; 436/106; 436/109; 436/127; 435/4; 435/6; 435/174] 6 Claims
OG exemplary drawing
 
1. A compound having a formula vii:
[(R1)(R2)(R3)Si—X-Z-CYNH]2Si (NHCYL-M)2  vii
wherein R1, R2 and R3 independently represents C1-C6 alkoxy, C1-C6 alkyl, phenyl, or aryl substituted with one or more groups selected from the group consisting of C1-C6 alkyl and C1-C6 alkoxy; L represents a linking group; X represents linear or branched C1-C20 alkyl or aryl substituted with one or more groups selected from the group consisting of C1-C6 alkyl and C1-C6 alkoxy, optionally substituted with one or more heteroatoms comprising oxygen, nitrogen, or sulfur; Y represents oxygen or sulfur; and Z represents oxygen or NH; and M represents a molecule, with the proviso that at least one of R1, R2, or R3 represents C1-C6 alkoxy.