US 7,482,025 B2
	Biomaterial derived from vertebrate liver tissue
Stephen F. Badylak, West Lafayette, Ind. (US)
Assigned to Purdue Research Foundation, West Lafayette, Ind. (US)
Filed on Feb. 10, 2004, as Appl. No. 10/775,386.
Application 10/775386 is a continuation of application No. 10/134416, filed on Apr. 29, 2002, granted, now 6,793,939.
Application 10/134416 is a continuation of application No. 09/319781, granted, now 6,379,710, previously published as PCT/US97/22727, filed on Dec. 10, 1997.
Claims priority of provisional application 60/032680, filed on Dec. 10, 1996.
Prior Publication US 2004/0157323 A1, Aug. 12, 2004
Int. Cl. A61K 35/407 (2006.01)

U.S. Cl. 424—553

21 Claims

1. A method for inducing the formation of endogenous tissue at a site in need of endogenous tissue growth in a warm-blooded vertebrate, the method comprising the step of implanting a graft composition comprising an extracellular matrix in an amount effective to induce endogenous tissue growth at the site in need of the tissue growth wherein the matrix comprises gelled liver basement membrane tissue of a warm-blooded vertebrate and wherein the liver basement membrane is substantially free of endogenous cells associated with said liver basement membrane.