US 7,476,533 B2
	Diagnostic devices for use in the assaying of biological fluids
William G Meathrel, York, Pa. (US); Herbert M. Hand, Sr., Bel Air, Md. (US); and Li-Hung Su, Loganville, Pa. (US)
Assigned to Adhesives Research, Inc., Glen Rock, Pa. (US)
Appl. No. 10/474,920 PCT Filed Apr. 19, 2002, PCT No. PCT/US02/12329 § 371(c)(1), (2), (4) Date Oct. 16, 2003, PCT Pub. No. WO02/085185, PCT Pub. Date Oct. 31, 2002.
Prior Publication US 2004/0115831 A1, Jun. 17, 2004
Int. Cl. G01N 33/53 (2006.01)

U.S. Cl. 435—287.2  [422/56; 422/57; 422/58; 422/61; 435/287.1; 435/4; 435/287.7; 435/287.9; 435/810; 436/514; 436/518; 436/169; 436/810]

26 Claims

1. In a lateral flow in-vitro diagnostic device comprising a housing, means in the housing to introduce a sample to be assayed in said device, means in said housing for fluid collection, and a backing strip having spaced apart first and second ends, the improvement comprising the backing strip having a surface with hydrophilic properties, said surface comprising either a hydrophilic heat-sealable adhesive or a hydrophilic pressure sensitive adhesive, wherein the adhesive increases the surface energy of a fluid flow path in the device and wherein the adhesive decreases the surface tension of a biological fluid flowing along the fluid flow path.