US 7,476,509 B2
Compounds and methods for modulating functions of nonclassical cadherins
Orest W Blaschuk, Westmount (Canada); and Stephanie D Michaud, Hull (Canada)
Assigned to Adherex Technologies Inc., Ottawa (Canada)
Filed on Nov. 14, 2003, as Appl. No. 10/714,564.
Claims priority of provisional application 60/426689, filed on Nov. 14, 2002.
Claims priority of provisional application 60/426551, filed on Nov. 14, 2002.
Prior Publication US 2004/0175361 A1, Sep. 09, 2004
Int. Cl. A61K 38/04 (2006.01); G01N 33/53 (2006.01)
U.S. Cl. 435—7.1  [530/327; 530/326; 530/329] 5 Claims
 
1. A cell adhesion modulating agent ranging in size from 6 to 15 amino acid residues that
(a) inhibits desmosomal cadherin-mediated cell adhesion; and
(b) consists essentially of the amino acid sequence Arg-Trp-Ala-Pro-Ile-Pro (SEQ ID NO: 2).