US 7,476,383 B2
	Antibody selective for DR4 and uses thereof
Tong Zhou, Birmingham, Ala. (US); Robert P. Kimberly, Birmingham, Ala. (US); William J. Koopman, Indian Springs, Ala. (US); Albert F. Lobuglio, Birmingham, Ala. (US); and Donald J. Buchsbaum, Montevallo, Ala. (US)
Assigned to The UAB Research Foundation, Birmingham, Ala. (US)
Filed on Oct. 31, 2002, as Appl. No. 10/286,132.
Application 10/286132 is a continuation in part of application No. PCT/US01/14151, filed on May 02, 2001.
Claims priority of provisional application 60/346402, filed on Nov. 01, 2001.
Claims priority of provisional application 60/201344, filed on May 02, 2000.
Prior Publication US 2003/0198637 A1, Oct. 23, 2003
Int. Cl. C07K 16/28 (2006.01); C07K 16/30 (2006.01); A61K 39/395 (2006.01)

U.S. Cl. 424—143.1  [424/138.1; 530/387.1; 530/388.22; 530/388.8; 530/350; 530/387.3; 435/334; 435/344]

54 Claims

1. A monoclonal antibody having the same epitope specificity as the antibody produced by hybridoma 2E12 having ATCC Accession Number PTA-3798.