US 7,473,800 B2
	Method of manufacturing acetic acid
Yasuo Hosono, Yokohama (Japan); Tadashi Matsumoto, Yokohama (Japan); Rei Sato, Yokohama (Japan); Takeshi Minami, Yokohama (Japan); Chieko Nagasawa, Yokohama (Japan); and Munenori Maekawa, Yokohama (Japan)
Assigned to Chiyoda Corporation, Yokohama-shi (Japan)
Appl. No. 10/548,521 PCT Filed Mar. 11, 2004, PCT No. PCT/JP2004/003248 § 371(c)(1), (2), (4) Date Sep. 09, 2005, PCT Pub. No. WO2004/080941, PCT Pub. Date Sep. 23, 2004.
Claims priority of application No. 2003-067896 (JP), filed on Mar. 13, 2003; application No. 2003-094905 (JP), filed on Mar. 31, 2003; and application No. 2003-095532 (JP), filed on Mar. 31, 2003.
Prior Publication US 2006/0281944 A1, Dec. 14, 2006
Int. Cl. C07C 51/12 (2006.01)

U.S. Cl. 562—519

21 Claims

1. A method of manufacturing acetic acid by carbonylating methanol with carbon monoxide by way of a heterogeneous catalytic reaction in a bubble column reactor, characterized in that the carbonylating reaction is conducted with a solid catalyst concentration of not less than 100 kg/m3 in terms of the reaction volume, wherein the partial pressure of carbon monoxide in the reactor is between 1.0 and 2.5 MPa and the exhaustion ratio of carbon monoxide is between 3 and 15% of the theoretical reaction volume of carbon monoxide, while the liquid superficial velocity is between 0.2 and 1.0 m/sec.