Patent Terms Extended Under 35 U.S.C.   156

   Certificates extending the terms of the following patents were issued
on September 2, 1998.

U.S. Patent No. 4,309,445; Granted January 5, 1982, to Wurtman et al.;
Owner of Record: Massachusetts Institute of Technology; Title:
D-Fenfluramine for Modifying Feeding Behavior; Classification: 514/654;
Product Trade Name: REDUX  (dexfenfluramine hydrochloride); Original
Expiration Date: June 16, 2000; Term Extended: 1,343 days; Extended
Expiration Date: February 19, 2004.

U.S. Patent No. 4,572,912; Granted February 25, 1986, to Takao Yoshioka
et al.; Owner of Record: Sankyo Company Limited; Title: Thiazolidine
Derivatives, Their Preparation and Compositions Containing Them;
Classification: 514/369; Product Trade Names: PRELAY  and REZULIN
(troglitazone); Original Expiration Date: August 28, 2004; Term
Extended: 1,534 days; Extended Expiration Date: November 9, 2008.

U.S. Patent No. 4,599,353; Granted July 8, 1986, to Laszlo Z. Bito;
Owner of Record: The Trustees of Columbia University in the City of New
York; Title: Use of Eicosanoids and Their Derivatives for Treatment of
Ocular Hypertension and Glaucoma; Classification: 514/530; Product Trade
Name: XALATAN Sterile Ophthalmic Solution   (latanoprost); Original
Expiration Date: July 8, 2003; Term Extended: 1,116 days; Extended
Expiration Date: July 28, 2009.

U.S. Patent No. 4,873,259; Granted October 10, 1989, to James B. Summers
et al.; Owner of Record: Abbott Laboratories; Title: Indole Benzofuran,
Benzothiophene Containing Lipoxygenase Inhibiting Compounds;
Classification: 514/433; Product Trade Name: ZYFLO   (zileuton);
Original Expiration Date: February 10, 2007; Term Extended: 1,398 days;
Extended Expiration Date: December 9, 2010.

U.S. Patent No. 4,895,841; Granted January 23, 1990, to Hachiro Sugimoto
et al.; Owner of Record: Eisai Co., Ltd.; Title: Cyclic Amine Compounds
with Activity Against Acetylcholinesterase; Classification: 514/212;
Product Trade Name: ARICEPT   (donepezl l hydrochloride); Original
Expiration Date: June 20, 2008; Term Extended: 888 days; Extended
Expiration Date: November 25, 2010.