Patent Terms Extended Under 35 U.S.C.   156

   Certificates extending the terms of the following patents were issued
on August 27, 1998.

U.S. Patent No. 4,863,908; Granted September 5, 1989, to Dario Chiarino
et al.; Owner of Record: Zambon Group, S.p.A.; Title: Mono(2-Ammonium-2-
Hydroxymethyl-1,3 Propanediol)(2R-Cis)-3-Methyloxiranyl)Phosphonate, Its
Preparation and Pharmaceutical Compositions Containing It; Classification:
514/76; Product Trade Name: MONUROL (fosfomycin tromethamine); Original
Expiration Date: February 23, 2005; Term Extended: 1,527 days;
Expiration of Extension: April 30, 2009.

U.S. Patent No. 4,870,086; Granted September 26, 1989, to Rune V.
Sandberg; Owner of Record: Astra Lakemedel Aktiebolag; Title: Optically
Pure Compound and a Process for its Preparation; Classification:
514/330; Product Trade Name: NAROPIN (ropivacaine HCl); Original
Expiration Date: November 24, 2006; Term Extended: 1,400 days;
Expiration Date of Extension: September 24, 2010.

U.S. Patent No. 4,943,569; Granted July 24, 1990, to Makoto Sunagawa et
al.; Owner of Record: Sumitomo Pharmaceuticals Company, Ltd.; Title:
-Lactam Compounds; Classification: 514/210; Product Trade Name:
MERREM I.V. (meropenem for injection); Original Expiration Date: July
24, 2007; Term Extended: 1,063 days; Expiration Date of Extension: June
21, 2010.

U.S. Patent No. 5,004,758; Granted April 2, 1991, to Jeffrey C. Boehm et
al.; Owner of Record: SmithKline Beecham Corporation; Title: Water
Soluble Camptothecin Analogs Useful for Inhibiting the Growth of Animal
Tumor Cells; Classification: 514/283; Product Trade Name: HYCAMTIN
(topotecan HCl) for Injection; Original Expiration Date: April 2, 2008;
Term Extended: 786 days; Expiration Date of Extension: May 20, 2010.

U.S. Patent No. 5,015,247; Granted May 14, 1991, to Gary K. Michelson;
Owner of Record: Karlin Technology Inc.; Title: Threaded Spinal Implant;
Classification: 606/61; Product Trade Name: BAK Interbody Fusion System;
Original Expiration Date: June 13, 2008; Term Extended: 829 days;
Expiration Date of Extension: September 20, 2010.

U.S. Patent No. 5,021,458; Granted June 4, 1991, to Tetsuya Maeda et
al.; Owner of Record: Kaken Pharmaceutical Co., Ltd.; Title: Amine
Derivatives and Fungicides Containing the Same; Classification: 514/655;
Product Trade Name: MENTAX (butenafine hydrochloride); Original
Expiration Date: June 4, 2008; Term Extended: 866 days; Expiration Date
of Extension: October 18, 2010.

U.S. Patent No. 5,089,480; Granted February 18, 1992, to Stephen P.
Gibson; Owner of Record: Pfizer Inc.; Title: Antiparasitic Agents;
Classification: 514/30; Product Trade Name: DECTOMAX (doramectin);
Original Expiration Date: February 18, 2009; Term Extended: 527 days;
Expiration Date of Extension: July 30, 2010.

U.S. Patent No. 5,116,863; Granted May 26, 1992, to Etsuo Oshima et al.;
Owner of Record: Kyowa Hakko Kogyo Co., Ltd.; Title: Dibenz[B,E]Oxepin
Derivative and Pharmaceutical Compositions Thereof; Classification:
514/450; Product Trade Name: PATANOL (olopatadine hydrochloride);
Original Expiration Date: May 26, 2009; Term Extended: 571 days;
Expiration Date of Extension: December 18, 2010.

U.S. Patent No. 5,162,504; Granted November 10, 1992, to Julius S.
Horoszewicz; Owner of Record: Cytogen Corporation; Title: Monoclonal
Antibodies to a New Antigenic Marker in Epithelial Prostatic Cells and
Serum of Prostatic Cancer Patients; Classification: 530/388.2; Product
Trade Name: ProstaScint (capromab pendetide); Original Expiration
Date: November 10, 2009; Term Extended: 352 days; Expiration Date of
Extension: September 28, 2012.