If I file a PCT application with RO/US, and if I provide the Request as a PDF, how does the bibliographic information get into the computer systems? Will it be manually entered by USPTO personnel?

Bibliographic information will be automatically loaded from the Request into the USPTO system if the Request is submitted as part of the PCT-EASY zip file. If the Request is submitted in PDF but not as part of the PCT-SAFE zip file, the information will be manually entered from the Request by the USPTO.

USPTO FAQ - Questions and Answers (2007JUN01)