Is an Application Data Sheet (ADS) required when submitting a new utility application?

No, it is not required to file a new utility application. However if the form-fillable ADS (SB14) is used, the data entered will be auto-loaded into USPTO backend systems, thus bypassing manual entry of data. The form-fillable ADS is available at US_ADS_Form_SB_14.

USPTO FAQ - Questions and Answers (2007JUN01)