| | This subclass is indented under subclass 1. Compounds which are carbohydrates or derivatives thereof,
i.e., those compounds which satisfy one of the three criteria set
forth below (unless otherwise indicated, figures are representative
examples only):Criterion 1: compounds whose monomeric units are polyhydroxy
mono-aldehydes [1, 2] or polyhydroxy mono-ketones [3,
4] having the formula Cn(H2O)n (wherein
n = 5 or 6 – subsequent references to "n" refer
to these values), i.e., "acyclic saccharides," of
which representative samples are:
![D-ribose [1]](c536s1-11-1.gif)
D-ribose [1] ![D-glucose [2]](c536s1-11-2.gif)
D-glucose [2] ![D-ribulose [3]](c536s1-11-3.gif)
D-ribulose [3] ![D-fructose [4] Criterion 2: the corresponding cyclic hemiacetals, i.e. 'cyclic saccharides' of which representative examples are:](c536s1-11-4.gif)
D-fructose [4] Criterion 2: the correspondingcyclic hemiacetals, i.e. "cyclic saccharides" of
which representative examples are:
![a-D-ribose D-ribofuranose [5]](c536s1-11-5.gif)
a-D-ribose D-ribofuranose [5] ![a-D-glucose D-glucopyranose [6]](c536s1-11-6.gif)
a-D-glucose D-glucopyranose [6] ![a-D-glucose D-glucopyranose [7]](c536s1-11-7.gif)
a-D-glucose D-glucopyranose [7] ![a-D-glucose D-glucopyranose [8] wherein: (i) figure [5] is the cyclic form of figure [1], (ii) figures [6-8] each depict, in a different way, a-D-glucose, which is one of the two cyclic forms of D-glucose shown in figure [2], (iii) figure [2] is a Fischer projection, figure [6] is a conformational projection, figure [7] is a Haworth projection, and figure [8] is a Mills projection, (iv) the number one carbon atom, the asterisked carbon atom, is the hemiacetal carbon and is also known as the anomeric carbon. Criterion 3: the derivatives of (1) or (2) wherein: (a) for acyclic saccharides, (i) the 5 or 6 carbon member skeleton and the carbonyl function are not destroyed, (ii) there are no fewer than (n - 2) total -OR moieties directly bonded to the carbon skeleton (wherein R is H or a group bonded to oxygen through carbon), (iii) no more than one oxygen atom is attached to any one carbon of the carbon skeleton, and structures [9-14] are illustrative:](c536s1-11-8.gif)
a-D-glucose D-glucopyranose [8] wherein:(i) figure [5] is the cyclic form of figure [1],
(ii) figures [6-8] each depict, in a different
way, a-D-glucose, which is one of the two cyclic forms of D-glucose
shown in figure [2], (iii) figure [2] is
a Fischer projection, figure [6] is a conformational
projection, figure [7] is a Haworth projection,
and figure [8] is a Mills projection, (iv) the
number one carbon atom, the asterisked carbon atom, is the hemiacetal
carbon and is also known as the anomeric carbon. Criterion 3:
the derivatives of (1) or (2) wherein: (a) for acyclic saccharides,
(i) the 5 or 6 carbon member skeleton and the carbonyl
function are not destroyed, (ii) there are no fewer than
(n - 2) total –OR moieties directly bonded to the carbon
skeleton (wherein R is H or a group bonded to oxygen through carbon),
(iii) no more than one oxygen atom is attached to any one carbon
of the carbon skeleton, and structures [9-14] are
illustrative:
![[9]](c536s1-11-9.gif)
[9] ![[10]](c536s1-11-10.gif)
[10] ![[11]](c536s1-11-11.gif)
[11] ![[12]](c536s1-11-12.gif)
[12] ![[13]](c536s1-11-13.gif)
[13] ![[14] (b) for cyclic saccharides, except for C-glycosyl compounds described in section, and (c) there can be substitution by moieties which do not destroy the cyclic saccharide structure as long as at least one -XH or -XR group is bonded directly to the hemiacetal/anomeric carbon (this carbon is denoted with an asterisk in the figures below), wherein X is -O-, -S-, or -NR subscript S- and R is H or a group bonded to X through carbon and R subscript S is a substituent which completes the valency of the nitrogen atom, and figures [15-18] represent the minimum structure necessary to constitute a cyclic saccharide derivative:](c536s1-11-14.gif)
[14] (b) for cyclicsaccharides, except for C-glycosyl compounds described
in section, and (c) there can be substitution by moieties which
do not destroy the cyclic saccharide structure as long as at least one
–XH or –XR group is bonded directly to the hemiacetal/anomeric carbon
(this carbon is denoted with an asterisk in the figures
below), wherein X is –O–, –S–,
or –NRS– and R is H or a
group bonded to X through carbon and RS is a
substituent which completes the valency of the nitrogen atom, and
figures [15-18] represent the minimum structure
necessary to constitute a cyclic saccharide derivative:
![[15] n=5](c536s1-11-15.gif)
[15] n=5 ![[16] n=6](c536s1-11-16.gif)
[16] n=6 ![[17] n=6](c536s1-11-17.gif)
[17] n=6 ![[18] n=6 wherein: - at least one of the R subscript 1 (where n = 5) or at least two of the R subscript 1 (where n = 6) must be -OR wherein R is H or a group bonded to the oxygen of -OR through carbon; and the representation of the bond between XR and the ring position 1 in ech of the structures [15-18] signifies an a (i.e., axial) or b (i.e., equatorial) configuration (c) for cyclic saccharide, C-glycosyl-type compounds (also known as C-glycosides) (i) C-glycosyl compounds will have the structure defined below [19-21]](c536s1-11-18.gif)
[18] n=6 wherein: - at leastone of the R1 (where n = 5) or at
least two of the R1 (where n = 6)
must be –OR wherein R is H or a group bonded to the oxygen
of –OR through carbon; and the representation of the
bond between XR and the ring position 1 in ech of the structures [15-18] signifies
an a (i.e., axial) or b (i.e., equatorial) configuration (c) for
cyclic saccharide, C-glycosyl-type compounds (also known as C-glycosides)
(i) C-glycosyl compounds will have the structure defined below [19-21]
![[19] n=5](c536s1-11-19.gif)
[19] n=5 ![[20] n=6](c536s1-11-20.gif)
[20] n=6 ![[21] n=6 wherein: - at least one of the R subscript 1 (where n = 5) or at least two of the R subscript 1 (where n = 6) must be -OR wherein R is H or group bonded to the oxygen of -OR through carbon; - R subscript 2, R subscript 3, and R subscript 4 alone or in combination can be any substituent which completes the valency of the carbon atom. (ii) 'C-glycoside', although often used in the art to represent this type compound, is a misnomer-'C-glycosyl' is the proper term.](c536s1-11-21.gif)
[21] n=6 wherein: - at leastone of the R1 (where n = 5) or at
least two of the R1 (where n = 6)
must be –OR wherein R is H or group bonded to the oxygen
of –OR through carbon; - R2, R3,
and R4 alone or in combination can be any substituent
which completes the valency of the carbon atom. (ii) "C-glycoside",
although often used in the art to represent this type compound,
is a misnomer–"C-glycosyl" is the proper
term.
| | (1)
Note. All statements in this sublass definition are intended
to be inclusive of all spatial and stereochemical configurations,
except if otherwise specified. |
| | (2)
Note. Oxygen heteroatom-containing cyclic compounds lacking
any –XH or –XR bonded to the anomeric carbon
of the cyclic structure are not carbohydrates/cyclic hemiacetals;
such compounds are tetrahydrofurans [22] or tetrohydropyrans [23,
24]:
![Tetrahydrofuran [22]](c536s1-11-22.gif)
Tetrahydrofuran [22] ![Tetrahydropyran [23]](c536s1-11-23.gif)
Tetrahydropyran [23] ![Tetrahydropyran [24]](c536s1-11-24.gif)
Tetrahydropyran [24] |
| | (3)
Note. Included within the scope of this class are compounds
wherein oxygens which are attached to carbons of the carbohydrate
skeleton are also attached to the same alkylidene or substitued
alkylidene groups. See, for example, structures [25-29].
![[25]](c536s1-11-25.gif)
[25] ![[26]](c536s1-11-26.gif)
[26] ![[27]](c536s1-11-27.gif)
[27] ![[28]](c536s1-11-28.gif)
[28] ![[29]](c536s1-11-29.gif)
[29] |
| | (4)
Note. Carbohydrate degradation products which contain fewer
than five carbon atoms in the carbohydrate moiety are not provided
for in this class, but are classified elsewhere in the chemical compound
area. |
| | (5)
Note. Alcohol, acid, and amine derivatives of carbohydrates
which are formed by an alcohol, carboxylic acid, or amine function
replacing the oxygen of the carbonyl group of an acyclic carbohydrate are
not provided for in this class, but are classified elsewhere. |
| | (6)
Note. The heteroatom of the cyclic carbohydrate must be an
oxygen. Compounds with different heteroatoms or compounds without
a heteroatom in the cyclic structure (e.g. inositol) are not classified
in this class; they are classified elsewhere. |
| | (7)
Note. Some names of common carbohydrates include:
Monosaccharides:
Fructose (Fru), Fucose (Fuc), Galactosamine (GalN), Galactose (Gal),
Glucosamine (GlcN), Glucose (Glc), Glucuronic acid (GlcA), Idose
(Ido), Mannose (Man), Neuraminic acid (e.g., Neu5Ac, etc.), Sialic
acid, Xylose (Xyl).
Oligosaccharides: Cyclodextrin,
Lactose (Lac), Maltose, Raffinose, Sialyl Lewis x (sLex),
Sucrose, Trehalose.
Homopolysaccharides (all
the monomeric units are the same): Amylose/Amylopectin,
Cellulose, Chitin/Chitosan, Dextran, Glucan, Inulin, Starch.
Heteropolysaccharides (different
monomers comprise the repeating unit): Algin/Alginic acid,
Bacterial/capsular polysaccharides; Glycosaminoglycans (Mucopolysaccharides
including Chondroitin sulfate, Dermatan sulfate, Heparin, Heparan
sulfate, Hyaluronic acid, Keratan sulfate); Gums, Mannans, Pectins,
Xylan. |
SEE OR SEARCH THIS CLASS, SUBCLASS:
| 22.1 | through 24.5, for nucleic acids and oligomeric or polymeric forms thereof,
including DNA or RNA fragments (e.g., genes, etc.) |
SEE OR SEARCH CLASS:
| 127, | Sugar, Starch, and Carbohydrates,
subclasses 36 through 41for hydrolysis of carbohydrates by nonbiochemical
methods wherein the process stops with such hydrolysis or is followed
by purification, concentration, or crystallization of the sugar
or sugar solution thereby produced. |
| 162, | Paper Making and Fiber Liberation, appropriate subclasses for liberating, recovering,
or purifying of cellulose fibers from natural sources. |
| 424, | Drug, Bio-Affecting and Body Treating Compositions,
subclass 1.73 for carbohydrates attached to radionuclides; subclasses
9.35-9.351 for carbohydrates attached to magnetic imaging agents;
and subclass 9.43 for carbohydrates attached to X-ray contrast imaging
agents. |
| 428, | Stock Material or Miscellaneous Articles,
subclasses 532 through 537.7for a nonstructural laminate containing a carbohydrate. |
| 435, | Chemistry: Molecular Biology and Microbiology,
subclasses 72 through 105for enzymatic or microbial processes for synthesizing
a saccharide containing compound; subclasses 274-279 for using an
enzyme or microorganism to recover or purify a carbohydrate material
from animal, plant, or microbial material. |
| 506, | Combinatorial Chemistry Technology: Method, Library,
Apparatus, for a carbohydrate library and a process of creating
said library. |
| 514, | Drug, Bio-Affecting and Body Treating Compositions,
subclasses 23 through 62for pharmaceutical and cosmetic compositions containing
a carbohydrate as the active ingredient. |
| 527, | Synthetic Resins or Natural Rubbers,
subclasses 300 through 315for a solid polymer derived from a carbohydrate
or derivative reactant and an ethylenic reactant, a SICP or a SPFI or
a process of preparing said polymer. |
| 530, | Chemistry: Natural Resins or Derivatives; Peptides
or Proteins; Lignins or Reaction Products Thereof,
subclasses 395 through 398for glycoproteins such as proteoglycans, mucins,
etc. |
| 544, | Organic Compounds, appropriate subclasses for purines and pyrimidines which
do not have a carbohydrate attached. |
| 549, | Organic Compounds,
subclass 315 for ascorbic acid; subclasses 356-428 for tetrahydropyrans;
and subclasses 429-509 for tetrahydrofurans. Such tetrahydropyrans
and tetrahydrofurans lack an –XH or –XR bonded
to what would be the anomeric carbon atom of a cyclic saccharide. |
| 562, | Organic Compounds,
subclasses 512 through 609for compounds wherein a carboxylic acid group has
replaced the carbonyl function of an acyclic carbohydrate, especially
subclass 597 for oxalic acid. |
| 564, | Organic Compounds, for compounds wherein an amine function has replaced
the carbonyl function of an acyclic carbohydrate. |
| 568, | Organic Compounds,
subclasses 852 through 872for compounds wherein an alcohol group has replaced
the carbonyl group of an acyclic carbohydrate. |
|